(Q45927250)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

0 references

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Steven C. Leiser

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Brian F Corbett

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Huai-Ping Ling

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Reka Nagy

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Nathalie Breysse

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Xiaohong Zhang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Anupam Hazra

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Andrew D Randall

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Andrew Wood

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Menelas N Pangalos

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Peter H Reinhart

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jeannie Chin

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

language of work or name

English

0 references

publication date

1 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

7020-7026

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

28 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6618875/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Neuropeptide Y: emerging evidence for a functional role in seizure modulation.

1 reference

12 December 2020

Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis.

1 reference

12 December 2020

Type I and type II Na(+) channel alpha-subunit polypeptides exhibit distinct spatial and temporal patterning, and association with auxiliary subunits in rat brain.

1 reference

12 December 2020

Surviving granule cells of the sclerotic human hippocampus have reduced Ca(2+) influx because of a loss of calbindin-D(28k) in temporal lobe epilepsy.

1 reference

12 December 2020

Theta oscillations in the hippocampus

1 reference

12 December 2020

Localization of beta-secretase memapsin 2 in the brain of Alzheimer's patients and normal aged controls

1 reference

12 December 2020

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

1 reference

12 December 2020

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

1 reference

12 December 2020

Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits

1 reference

12 December 2020

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

1 reference

12 December 2020

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

1 reference

12 December 2020

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

1 reference

12 December 2020

Neurobehavioral characterization of APP23 transgenic mice with the SHIRPA primary screen

1 reference

12 December 2020

beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

1 reference

12 December 2020

High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease

1 reference

12 December 2020

Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

1 reference

12 December 2020

Incidence and predictors of seizures in patients with Alzheimer's disease

1 reference

12 December 2020

Prevalence and causes of seizures at the time of diagnosis of probable Alzheimer's disease.

1 reference

12 December 2020

The distribution and targeting of neuronal voltage-gated ion channels

1 reference

12 December 2020

Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain.

1 reference

12 December 2020

1 reference

12 December 2020

BACE1 gene deletion: impact on behavioral function in a model of Alzheimer's disease.

1 reference

12 December 2020

Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides

1 reference

12 December 2020

Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis.

1 reference

12 December 2020

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

1 reference

12 December 2020

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation

1 reference

12 December 2020

Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

1 reference

12 December 2020

BACE1 regulates voltage-gated sodium channels and neuronal activity

1 reference

12 December 2020

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

1 reference

12 December 2020

Loss of astrocytic domain organization in the epileptic brain.

1 reference

12 December 2020

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

1 reference

12 December 2020

Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation

1 reference

12 December 2020

Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy.

1 reference

12 December 2020

What is remembered? Role of attention on the encoding and retrieval of hippocampal representations.

1 reference

12 December 2020

Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain.

1 reference

12 December 2020

BACE1 deficiency causes altered neuronal activity and neurodegeneration

1 reference

12 December 2020

BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

1 reference

12 December 2020

Alzheimer's secretases regulate voltage-gated sodium channels

1 reference

12 December 2020

Ion channel voltage sensors: structure, function, and pathophysiology

1 reference

12 December 2020

A manifold of spatial maps in the brain

1 reference

12 December 2020

The genetics of Alzheimer disease: back to the future

1 reference

12 December 2020

Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network

1 reference

12 December 2020

Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons

1 reference

12 December 2020

Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit

1 reference

12 December 2020

Reduced sodium channel Na(v)1.1 levels in BACE1-null mice

1 reference

12 December 2020

Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

1 reference

12 December 2020

Hippocampus and neocortex: recognition and spatial memory

1 reference

12 December 2020

Oscillations and hippocampal-prefrontal synchrony

1 reference

12 December 2020

Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model

1 reference

12 December 2020

Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment

1 reference

12 December 2020

Neurotoxicity of amyloid β-protein: synaptic and network dysfunction

1 reference

12 December 2020

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

1 reference

12 December 2020

The sodium channel from rat brain. Separation and characterization of subunits.

1 reference

12 December 2020

1 reference

12 December 2020

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

1 reference

12 December 2020

Deficits in memory and hippocampal long-term potentiation in mice with reduced calbindin D28K expression.

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

12 December 2020

10.1523/JNEUROSCI.2325-12.2013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23595759%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference