(Q46198058)

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Mechanism of zinc(II)-promoted amyloid formation: zinc(II) binding facilitates the transition from the partially alpha-helical conformer to aggregates of amyloid beta protein(1-28).

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18 January 2020

Mechanism of zinc(II)-promoted amyloid formation: zinc(II) binding facilitates the transition from the partially alpha-helical conformer to aggregates of amyloid beta protein(1-28) (English)

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18 January 2020

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18 January 2020

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Christine Talmard

1

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18 January 2020

Rodrigue Leuma Yona

2

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18 January 2020

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13 December 2008

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18 January 2020

Journal of Biological Inorganic Chemistry

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18 January 2020

14

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18 January 2020

3

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18 January 2020

449-455

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18 January 2020

https://scigraph.springernature.com/pub.10.1007/s00775-008-0461-9

0 references

Therapeutic strategies for human amyloid diseases

1 reference

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21 January 2018

Protein misfolding, functional amyloid, and human disease

1 reference

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21 January 2018

Functional amyloid--from bacteria to humans.

1 reference

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21 January 2018

1 reference

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21 January 2018

The Yin and Yang of protein folding

1 reference

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21 January 2018

Amyloid fibrils from the viewpoint of protein folding

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis

1 reference

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21 January 2018

Kinetic studies of amyloid beta-protein fibril assembly. Differential effects of alpha-helix stabilization

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

1 reference

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21 January 2018

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

1 reference

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21 January 2018

Rapid induction of Alzheimer A beta amyloid formation by zinc.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Interaction of the human prion PrP(106-126) sequence with copper(II), manganese(II), and zinc(II): NMR and EPR studies

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Human Abeta1-42 reduces iron-induced toxicity in rat cerebral cortex

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

New insights on how metals disrupt amyloid beta-aggregation and their effects on amyloid-beta cytotoxicity

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Metal ion-dependent effects of clioquinol on the fibril growth of an amyloid {beta} peptide

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Beta-amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Zinc-amyloid beta interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Zinc binding to amyloid-beta: isothermal titration calorimetry and Zn competition experiments with Zn sensors.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Binding of zinc(II) and copper(II) to the full-length Alzheimer's amyloid-beta peptide

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Characterization of the ZnII binding to the peptide amyloid-beta1-16 linked to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Solution 1H NMR investigation of Zn2+ and Cd2+ binding to amyloid-beta peptide (Abeta) of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Metal binding in amyloid beta-peptides shows intra- and inter-peptide coordination modes

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

NMR reveals anomalous copper(II) binding to the amyloid Abeta peptide of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

High-resolution NMR studies of the zinc-binding site of the Alzheimer's amyloid beta-peptide.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

NMR studies of the Zn2+ interactions with rat and human beta-amyloid (1-28) peptides in water-micelle environment.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Structural and thermodynamical properties of CuII amyloid-beta16/28 complexes associated with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Measurement of protein using bicinchoninic acid

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Zinc Binding to Alzheimer's Aβ(1–16) Peptide Results in Stable Soluble Complex

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Zinc binding properties of the amyloid fragment Aβ(1–16) studied by electrospray-ionization mass spectrometry

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Interaction of α-Synuclein with Divalent Metal Ions Reveals Key Differences: A Link between Structure, Binding Specificity and Fibrillation Enhancement

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0461-9

21 January 2018

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aluminium, iron, zinc and copper influence the in vitro formation of amyloid fibrils of Abeta42 in a manner which may have consequences for metal chelation therapy in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of Abeta conformation on the metal affinity and aggregation mechanism studied by circular dichroism spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta peptide forms monomeric complexes with Cu(II) and Zn(II) prior to aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Examining the zinc binding site of the amyloid-beta peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc Lowers Amyloid-β Toxicity by Selectively Precipitating Aggregation Intermediates†

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metal-mediated formation of fibrillar ABri amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the binding of Cu(II) and Zn(II) to transthyretin: effects on amyloid formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19083027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00775-008-0461-9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19083027%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19083027%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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