(Q46205464)

20 December 2017

title

Development of quantitative molecular clinical end points for siRNA clinical trials (English)

1 reference

20 December 2017

author

Irwin McLean

6

1 reference

20 December 2017

Christopher H. Contag

Christopher H Contag

7

0 references

Leonard Milstone

9

Leonard M Milstone

1 reference

20 December 2017

Robyn P Hickerson

1

Robyn P Hickerson

1 reference

20 December 2017

Roger L Kaspar

10

Roger L Kaspar

1 reference

20 December 2017

Lana N Pho

3

Lana N Pho

1 reference

20 December 2017

Devin Leake

8

Devin Leake

1 reference

20 December 2017

author name string

Sancy A Leachman

2

1 reference

20 December 2017

Emilio Gonzalez-Gonzalez

4

1 reference

20 December 2017

Frances J D Smith

5

1 reference

20 December 2017

language of work or name

English

0 references

publication date

30 December 2010

1 reference

20 December 2017

Journal of Investigative Dermatology

published in

1 reference

20 December 2017

volume

131

1 reference

20 December 2017

issue

5

1 reference

20 December 2017

page(s)

1029-1036

1 reference

20 December 2017

https://scigraph.springernature.com/pub.10.1038/jid.2010.372

exact match

0 references

cites work

An analysis of select pathogenic messages in lesional and non-lesional psoriatic skin using non-invasive tape harvesting

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Stable suppression of tumorigenicity by virus-mediated RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

The promises and pitfalls of RNA-interference-based therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Interfering with disease: a progress report on siRNA-based therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Knocking down disease with siRNAs

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Determinants of specific RNA interference-mediated silencing of human beta-globin alleles differing by a single nucleotide polymorphism

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

The business of RNAi therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Gene therapy progress and prospects: the skin--easily accessible, but still far away

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Single-nucleotide-specific siRNA targeting in a dominant-negative skin model

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Stability study of unmodified siRNA and relevance to clinical use.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Strategies for silencing human disease using RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Allele-specific silencing of the dominant disease allele in sialuria by RNA interference.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Keratins and skin disorders

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Clinical and pathological features of pachyonychia congenita

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Disease severity correlates with position of keratin point mutations in patients with epidermolysis bullosa simplex

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

10 years experience of the Dermatology Life Quality Index (DLQI).

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Allele-specific silencing of dominant disease genes

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Five siRNAs targeting three SNPs may provide therapy for three-quarters of Huntington's disease patients

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Methotrexate induces differentiation of human keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Designing siRNA that distinguish between genes that differ by a single nucleotide

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

The Molecular Genetics of Keratin Disorders

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Development of therapeutic siRNAs for pachyonychia congenita

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

The genetic basis of pachyonychia congenita.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Rapid, high-quality and epidermal-specific isolation of RNA from human skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Delivery and inhibition of reporter genes by small interfering RNAs in a mouse skin model

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Knocking down barriers: advances in siRNA delivery

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Use of RT-PCR and DNA microarrays to characterize RNA recovered by non-invasive tape harvesting of normal and inflamed skin.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.372

7 January 2021

Identifiers

DOI

10.1038/JID.2010.372

1 reference

20 December 2017

1 reference

20 December 2017