(Q46377922)

21 December 2017

title

AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts (English)

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21 December 2017

author

Daniel Iglesias-Serret

3

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21 December 2017

Joan Gil

10

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21 December 2017

Cristina Moncunill-Massaguer

object named as

Cristina Moncunill-Massaguer

2

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author name string

Diana M González-Gironès

1

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21 December 2017

Ana M Cosialls

4

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21 December 2017

Alba Pérez-Perarnau

5

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21 December 2017

Claudia M Palmeri

6

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21 December 2017

Camila Rubio-Patiño

7

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21 December 2017

Andreas Villunger

8

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21 December 2017

Gabriel Pons

9

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21 December 2017

publication date

1 August 2013

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21 December 2017

published in

Apoptosis

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21 December 2017

volume

18

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21 December 2017

issue

8

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21 December 2017

page(s)

1008-1016

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21 December 2017

https://scigraph.springernature.com/pub.10.1007/s10495-013-0850-6

exact match

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cites work

Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes

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AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.

21 January 2018

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Acadesine induces apoptosis in B cells from mantle cell lymphoma and splenic marginal zone lymphoma

21 January 2018

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Activation of adenosine monophosphate activated protein kinase inhibits growth of multiple myeloma cells

21 January 2018

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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy

21 January 2018

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5-Aminoimidazole-4-carboxamide riboside induces apoptosis in Jurkat cells, but the AMP-activated protein kinase is not involved.

21 January 2018

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Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies

21 January 2018

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AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase

21 January 2018

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Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells

21 January 2018

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5'-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells.

21 January 2018

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Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer.

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

21 January 2018

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Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress

21 January 2018

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p53 and E2f: partners in life and death

21 January 2018

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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

21 January 2018

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The BCL-2 protein family: opposing activities that mediate cell death

21 January 2018

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Identification of aneuploidy-selective antiproliferation compounds

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.

21 January 2018

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5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

21 January 2018

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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

21 January 2018

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Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways

21 January 2018

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Glycogen synthase kinase-3β is involved in ligand-dependent activation of transcription and cellular localization of the glucocorticoid receptor

21 January 2018

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Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1

21 January 2018

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Bub1 up-regulation and hyperphosphorylation promote malignant transformation in SV40 tag-induced transgenic mouse models.

21 January 2018

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AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

21 January 2018

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Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate

21 January 2018

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AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF

21 January 2018

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An E2F1-dependent gene expression program that determines the balance between proliferation and cell death

21 January 2018

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Role of 5'-adenosine monophosphate-activated protein kinase in cell survival and death responses in neurons.

21 January 2018

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Inhibition of AMP-activated protein kinase α (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1.

21 January 2018

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AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

21 January 2018

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Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

21 January 2018

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2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0850-6

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0850-6

SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0850-6

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0850-6

10.1007/S10495-013-0850-6

21 January 2018

Identifiers

DOI

1 reference

21 December 2017

1 reference

21 December 2017