(Q46440592)

English

Towards an animal model of an antipsychotic drug-resistant cognitive impairment in schizophrenia: scopolamine induces abnormally persistent latent inhibition, which can be reversed by cognitive enhancers but not by antipsychotic drugs

scientific article published on 8 August 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

Towards an animal model of an antipsychotic drug-resistant cognitive impairment in schizophrenia: scopolamine induces abnormally persistent latent inhibition, which can be reversed by cognitive enhancers but not by antipsychotic drugs (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

0 references

1 reference

based on heuristic

inferred from title

cognitive dysfunction

1 reference

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author name string

Segev Barak

1

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

Ina Weiner

2

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

publication date

8 August 2008

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

The International Journal of Neuropsychopharmacology

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

12

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

2

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

227-241

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

Scopolamine selectively disrupts the acquisition of contextual fear conditioning in rats

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N-Methyl-D-aspartate receptors as a target for improved antipsychotic agents: novel insights and clinical perspectives

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Locomotion and stereotypy induced by scopolamine: contributions of muscarinic receptors near the pedunculopontine tegmental nucleus.

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Schizophrenia and the alpha7 nicotinic acetylcholine receptor

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Measurement and Treatment Research to Improve Cognition in Schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia.

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A theory of attention: Variations in the associability of stimuli with reinforcement

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The visual search analogue of latent inhibition: implications for theories of irrelevant stimulus processing in normal and schizophrenic groups

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Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia

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N-desmethylclozapine, a major metabolite of clozapine, increases cortical acetylcholine and dopamine release in vivo via stimulation of M1 muscarinic receptors

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Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization

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Effects of clozapine on memory function in the rat neonatal hippocampal lesion model of schizophrenia

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D-cycloserine facilitates extinction of learned fear: effects on reacquisition and generalized extinction

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Glutamate-based therapeutic approaches: inhibitors of glycine transport

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Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor.

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Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study

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Effects of ketamine in normal and schizophrenic volunteers

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NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development

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Toward a neuro-cognitive animal model of the cognitive symptoms of schizophrenia: disruption of cortical cholinergic neurotransmission following repeated amphetamine exposure in attentional task-performing, but not non-performing, rats

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D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats.

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Obsessive-compulsive disorder patients display enhanced latent inhibition on a visual search task.

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Nicotine blocks latent inhibition in rats: evidence for a critical role of increased functional activity of dopamine in the mesolimbic system at conditioning rather than pre-exposure.

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Pharmacologic interactions between the muscarinic cholinergic and dopaminergic systems in the modulation of prepulse inhibition in rats

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Recent advances in the phencyclidine model of schizophrenia

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Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action

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Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum

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Differential effects of haloperidol, clozapine and olanzapine on learning and memory functions in mice.

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Galantamine and donepezil attenuate pharmacologically induced deficits in prepulse inhibition in rats

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D-serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia

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Glycine(B) receptor antagonists and partial agonists prevent memory deficits in inhibitory avoidance learning.

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Glutamatergic neurotransmission modulation and the mechanisms of antipsychotic atypicality

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Effects of anticholinergic drugs selective for muscarinic receptor subtypes on prepulse inhibition in mice.

1 reference

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High acetylcholine levels set circuit dynamics for attention and encoding and low acetylcholine levels set dynamics for consolidation

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The role of muscarinic and nicotinic cholinergic neurotransmission in aversive conditioning: comparing pavlovian fear conditioning and inhibitory avoidance

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The role of acetylcholine in learning and memory

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Glycine-evoked release of [3H]acetylcholine from rat striatal slices is independent of the NMDA receptor

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Treatment of cognitive impairment in early psychosis: a comparison of risperidone and haloperidol in a large long-term trial

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The role of negative symptoms and cognitive dysfunction in schizophrenia outcome.

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Physostigmine. Its use in acute anticholinergic syndrome with antidepressant and antiparkinson drugs

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Enhanced visual latent inhibition in obsessive-compulsive disorder

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Scopolamine disrupts visual reversal without affecting the first discrimination

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Amphetamine psychosis: a "model" schizophrenia mediated by catecholamines.

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D-cycloserine, a modulator of the N-methyl-D-aspartate receptor, improves spatial learning in rats treated with muscarinic antagonist.

1 reference

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Dose-response curves and time-course effects of selected anticholinergics on locomotor activity in rats

1 reference

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1 reference

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Systemic administration of MK-801 produces an abnormally persistent latent inhibition which is reversed by clozapine but not haloperidol.

1 reference

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Abnormally persistent latent inhibition induced by MK801 is reversed by risperidone and by positive modulators of NMDA receptor function: differential efficacy depending on the stage of the task at which they are administered

1 reference

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Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site

1 reference

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D-cycloserine attenuates scopolamine-induced learning and memory deficits in rats

1 reference

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The latent inhibition model dissociates between clozapine, haloperidol, and ritanserin.

1 reference

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Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding

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Effect of a M1 allosteric modulator on scopolamine-induced amnesia.

1 reference

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Abnormally persistent latent inhibition induced by lesions to the nucleus accumbens core, basolateral amygdala and orbitofrontal cortex is reversed by clozapine but not by haloperidol

1 reference

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Muscarinic receptors in schizophrenia.

1 reference

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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Glycine modulation of NMDA-evoked release of [3H]acetylcholine and [3H]dopamine from rat striatal slices.

1 reference

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7 January 2021

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Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set-shifting

1 reference

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7 January 2021

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1 reference

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Cholinergic effects on fear conditioning I: the degraded contingency effect is disrupted by atropine but reinstated by physostigmine

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Towards a muscarinic hypothesis of schizophrenia.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain

1 reference

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7 January 2021

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Acute but not chronic activation of the NMDA-coupled glycine receptor with D-cycloserine facilitates learning and retention.

1 reference

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7 January 2021

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Anticholinergic syndrome after anesthesia: a case report and review

1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

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The effects of phencyclidine on latent inhibition in taste aversion conditioning: differential effects of preexposure and conditioning

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

D-cycloserine, a glycine site agonist, reverses working memory failure by hippocampal muscarinic receptor blockade in rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

N-methyl-D-aspartate-evoked release of acetylcholine from the medial septum/diagonal band of rat brain.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

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Role of tegmental cholinergic neurons in dopaminergic activation, antimuscarinic psychosis and schizophrenia

1 reference

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7 January 2021

based on heuristic

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Haloperidol- and clozapine-induced enhancement of latent inhibition with extended conditioning: implications for the mechanism of action of neuroleptic drugs.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption and potentiation of latent inhibition by risperidone: the latent inhibition model of atypical antipsychotic action

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Facilitation of the expression but not the acquisition of latent inhibition by haloperidol in rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

The switching model of latent inhibition: an update of neural substrates

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

The "two-headed" latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Deficit of NMDA receptor activation in CA1 hippocampal area of aged rats is rescued by D-cycloserine

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Neural substrates of latent inhibition: the switching model

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Does negative symptom change relate to neurocognitive change in schizophrenia? Implications for targeted treatments.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

D-cycloserine, a novel cognitive enhancer, improves spatial memory in aged rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased amphetamine-induced locomotion and improved latent inhibition in mice mutant for the M5 muscarinic receptor gene found in the human 15q schizophrenia region.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Scopolamine induces disruption of latent inhibition which is prevented by antipsychotic drugs and an acetylcholinesterase inhibitor.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Pre-training blocks the improving effect of tetrahydroaminoacridine and D-cycloserine on spatial navigation performance in aged rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

D-cycloserine, a positive modulator of the N-methyl-D-aspartate receptor, enhances performance of learning tasks in rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Amphetamine psychosis: behavioral and biochemical aspects.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Management of the negative symptoms of schizophrenia: new treatment options

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Scopolamine and Pavlovian fear conditioning in rats: dose-effect analysis.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of anticholinergic load with impairment of complex attention and memory in schizophrenia

1 reference

https://api.crossref.org/works/10.1017%2FS1461145708009176

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1017/S1461145708009176

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18687163

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