(Q46685509)

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Pharmacodynamic and/or pharmacokinetic characteristics of interactions between loreclezole and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

Pharmacodynamic and/or pharmacokinetic characteristics of interactions between loreclezole and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

pharmacodynamics

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Jarogniew Łuszczki

1

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

Stanisław Jerzy Czuczwar

4

object named as

Stanislaw J Czuczwar

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

Neville Ratnaraj

2

object named as

Neville Ratnaraj

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

author name string

Philip N Patsalos

3

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

publication date

2 September 2005

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

Epilepsy Behavior

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

7

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

4

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

639-651

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

Early identification of refractory epilepsy

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The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit

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Loreclezole enhances apparent desensitization of recombinant GABAA receptor currents

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In vivo studies on the mechanism of action of the broad spectrum anticonvulsant loreclezole

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A double-blind, placebo-controlled evaluation of the efficacy and safety of loreclezole as add-on therapy in patients with uncontrolled partial seizures

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7 January 2021

Long-term evaluation of the efficacy and safety of loreclezole as add-on therapy in patients with uncontrolled partial seizures: a 1-year open follow-up

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7 January 2021

Isobolographic and subthreshold methods in the detection of interactions between oxcarbazepine and conventional antiepileptics--a comparative study

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Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

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7 January 2021

The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. III. Pentylenetetrazole seizure models

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7 January 2021

Pharmacological and behavioral characteristics of interactions between vigabatrin and conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis

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7 January 2021

Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis

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7 January 2021

Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis.

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Modulation of morphine antinociception by peripheral [Leu5]enkephalin: a synergistic interaction.

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The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. IV. Protective indices

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Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons

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Block of cloned human T-type calcium channels by succinimide antiepileptic drugs.

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On the action of the anti-absence drug ethosuximide in the rat and cat thalamus.

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Block of Thalamic T-Type Ca(2+) Channels by Ethosuximide Is Not the Whole Story.

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Identifiers

10.1016/J.YEBEH.2005.07.007

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16140589

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