(Q46738656)

English

Relationship and prognostic significance of phospho-(serine 166)-murine double minute 2 and Akt activation in node-negative breast cancer with regard to p53 expression

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

Relationship and prognostic significance of phospho-(serine 166)-murine double minute 2 and Akt activation in node-negative breast cancer with regard to p53 expression (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

author name string

K J Schmitz

1

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

F Grabellus

2

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

R Callies

3

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

J Wohlschlaeger

4

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

F Otterbach

5

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

R Kimmig

6

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

B Levkau

7

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

K W Schmid

8

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

H A Baba

9

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

publication date

6 October 2005

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

Virchows Archiv

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

448

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

1

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

16-23

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

https://scigraph.springernature.com/pub.10.1007/s00428-005-0086-0

0 references

DNA amplifications at 20q13 and MDM2 define distinct subsets of evolved breast and ovarian tumours

1 reference

https://api.crossref.org/works/10.1007%2FS00428-005-0086-0

21 January 2018

Clinical relevance of immunohistochemical expression of p53-targeted gene products mdm-2, p21 and bcl-2 in breast carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS00428-005-0086-0

21 January 2018

Overexpression of MDM2 oncoprotein correlates with possession of estrogen receptor alpha and lack of MDM2 mRNA splice variants in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MDM2 gene amplification database

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic kinase signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitosis counting--a need for reappraisal

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDM2 and prognosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mdm2 gene alterations and mdm2 protein expression in breast carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of p53 stability by Mdm2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular survival: a play in three Akts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic relevance of activated Akt kinase in node-negative breast cancer: a clinicopathological study of 99 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mdm2 promotes the rapid degradation of p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p21/waf1/cip1 and mdm-2 expression in breast carcinoma patients as related to prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear exclusion of p53 in a subset of tumors requires MDM2 function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt enhances Mdm2-mediated ubiquitination and degradation of p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: an alternative pathway to non-small-cell lung cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16208531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00428-005-0086-0

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16208531

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