(Q46753862)

24 December 2017

title

Pyruvate Kinase M2 Modulates Esophageal Squamous Cell Carcinoma Chemotherapy Response by Regulating the Pentose Phosphate Pathway (English)

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24 December 2017

esophageal squamous cell carcinoma

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1 reference

1

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24 December 2017

Masaki Mori

10

Masaki Mori

1 reference

24 December 2017

Yuichiro Doki

11

Yuichiro Doki

1 reference

24 December 2017

Yukinori Kurokawa

6

Yukinori Kurokawa

1 reference

24 December 2017

Shuji Takiguchi

9

Shuji Takiguchi

1 reference

24 December 2017

Yasuhiro Miyazaki

3

Yasuhiro Miyazaki

1 reference

24 December 2017

Tomoki Makino

4

Tomoki Makino

1 reference

24 December 2017

Kiyokazu Nakajima

8

Kiyokazu Nakajima

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24 December 2017

Hiroshi Miyata

2

Hiroshi Miyata

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24 December 2017

author name string

Tsuyoshi Takahashi

5

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24 December 2017

Makoto Yamasaki

7

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24 December 2017

publication date

26 March 2015

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24 December 2017

Annals of Surgical Oncology

published in

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24 December 2017

volume

22 Suppl 3

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24 December 2017

page(s)

S1461-8

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24 December 2017

https://scigraph.springernature.com/pub.10.1245/s10434-015-4522-3

exact match

0 references

cites work

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Biomarkers for predicting the response of esophageal squamous cell carcinoma to neoadjuvant chemoradiation therapy

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A randomized trial comparing postoperative adjuvant chemotherapy with cisplatin and 5-fluorouracil versus preoperative chemotherapy for localized advanced squamous cell carcinoma of the thoracic esophagus (JCOG9907).

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Tumor budding in tumor invasive front predicts prognosis and survival of patients with esophageal squamous cell carcinomas receiving neoadjuvant chemotherapy.

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Targeting cancer metabolism: a therapeutic window opens

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The Warburg effect: insights from the past decade

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Otto Warburg's contributions to current concepts of cancer metabolism

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Understanding metabolic regulation and its influence on cell physiology

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Targeting glucose metabolism in patients with cancer

21 January 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

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Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

21 January 2018

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Cancer metabolism: key players in metabolic reprogramming

21 January 2018

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PKM2, a Central Point of Regulation in Cancer Metabolism

21 January 2018

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Pyruvate kinase type M2 and its role in tumor growth and spreading

21 January 2018

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

21 January 2018

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Emerging roles of PKM2 in cell metabolism and cancer progression

21 January 2018

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Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer

21 January 2018

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Pyruvate kinase M2 is a novel diagnostic marker and predicts tumor progression in human biliary tract cancer

21 January 2018

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Decreased pyruvate kinase M2 activity linked to cisplatin resistance in human gastric carcinoma cell lines

21 January 2018

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Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model

21 January 2018

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Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice

21 January 2018

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Regulation of cancer cell metabolism

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Targeting cancer metabolism

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

21 January 2018

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Pyruvate kinase M2: multiple faces for conferring benefits on cancer cells.

21 January 2018

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Metabolic pathway alterations that support cell proliferation.

21 January 2018

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Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

21 January 2018

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Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression

21 January 2018

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The pentose phosphate pathway and cancer

21 January 2018

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Regulation of the pentose phosphate pathway in cancer

21 January 2018

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New aspects of the Warburg effect in cancer cell biology

21 January 2018

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PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

21 January 2018

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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

21 January 2018

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Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme

21 January 2018

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Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells

21 January 2018

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10.1245/S10434-015-4522-3

21 January 2018

Identifiers

DOI

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24 December 2017

Dimensions Publication ID

1043507659

0 references

1 reference

24 December 2017