(Q46772716)

25 December 2017

title

Molecular determinants of Akt-induced keratinocyte transformation (English)

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25 December 2017

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Ramón García-Escudero

7

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25 December 2017

Jesus M. Paramio

12

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25 December 2017

author name string

C Segrelles

1

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25 December 2017

M Moral

2

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25 December 2017

M Fernanda Lara

3

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25 December 2017

S Ruiz

4

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25 December 2017

M Santos

5

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25 December 2017

H Leis

6

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25 December 2017

A B Martínez-Cruz

8

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25 December 2017

J Martínez-Palacio

9

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25 December 2017

P Hernández

10

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25 December 2017

C Ballestín

11

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25 December 2017

language of work or name

English

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publication date

1 February 2006

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25 December 2017

published in

Oncogene

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25 December 2017

volume

25

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25 December 2017

issue

8

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25 December 2017

page(s)

1174-1185

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25 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209155

exact match

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cites work

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter

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AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression

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Cyclin D1 over-expression correlates with beta-catenin activation, but not with H-ras mutations, and phosphorylation of Akt, GSK3 beta and ERK1/2 in mouse hepatic carcinogenesis.

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PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

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Targeting the PI3K-Akt pathway in human cancer: rationale and promise

21 January 2018

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A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

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21 January 2018

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21 January 2018

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Frequent genetic and biochemical alterations of the PI 3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma

21 January 2018

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21 January 2018

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p53 associates with and targets Delta Np63 into a protein degradation pathway

21 January 2018

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Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas

21 January 2018

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Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

21 January 2018

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Functional link between retinoblastoma family of proteins and the Wnt signaling pathway in mouse epidermis

21 January 2018

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The expression of keratin k10 in the basal layer of the epidermis inhibits cell proliferation and prevents skin tumorigenesis

21 January 2018

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21 January 2018

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21 January 2018

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Functional roles of Akt signaling in mouse skin tumorigenesis.

21 January 2018

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Akt mediates an angiogenic switch in transformed keratinocytes

21 January 2018

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21 January 2018

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Dominant negative p63 isoform expression in head and neck squamous cell carcinoma

21 January 2018

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

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HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Aberrant p21(CIP1/WAF1) protein accumulation in head-and-neck cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Caught up in a Wnt storm: Wnt signaling in cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

p53, p63 and p73 expression in squamous cell carcinomas of the head and neck and their response to cisplatin exposure.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

DeltaNp63 induces beta-catenin nuclear accumulation and signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Early overexpression of cyclin D1 protein in mouse skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

TCF transcription factors: molecular switches in carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Function and importance of p63 in normal oral mucosa and squamous cell carcinoma of the head and neck

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Relationship of p53 overexpression to other cell cycle regulatory proteins in oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209155

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209155

1 reference

25 December 2017

Dimensions Publication ID

1036740690

0 references

1 reference

25 December 2017