(Q46874668)

26 December 2017

title

Regulatory effects of mammalian target of rapamycin-mediated signals in the generation of arsenic trioxide responses (English)

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26 December 2017

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9

Martin S Tallman

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26 December 2017

4

Barbara Kroczynska

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26 December 2017

author name string

Jessica K Altman

1

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26 December 2017

Patrick Yoon

2

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26 December 2017

Efstratios Katsoulidis

3

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26 December 2017

Antonella Sassano

5

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26 December 2017

Amanda J Redig

6

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26 December 2017

Heather Glaser

7

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26 December 2017

Alison Jordan

8

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26 December 2017

Nissim Hay

10

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26 December 2017

Leonidas C Platanias

11

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26 December 2017

language of work or name

English

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publication date

29 November 2007

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26 December 2017

Journal of Biological Chemistry

published in

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26 December 2017

volume

283

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26 December 2017

issue

4

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26 December 2017

page(s)

1992-2001

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26 December 2017

Arsenic trioxide: new clinical experience with an old medication in hematologic malignancies

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Arsenic trioxide: its role in acute promyelocytic leukemia and potential in other hematologic malignancies

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United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia

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Biology of chronic myeloid leukemia and possible therapeutic approaches to imatinib-resistant disease

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Arsenic derivatives in hematologic malignancies: a role beyond acute promyelocytic leukemia?

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Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase

21 January 2018

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Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage

21 January 2018

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Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells

21 January 2018

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Programmed cell death-4 tumor suppressor protein contributes to retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells.

21 January 2018

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Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide

21 January 2018

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Activation of the mitogen- and stress-activated kinase 1 by arsenic trioxide

21 January 2018

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ASK1 is activated by arsenic trioxide in leukemic cells through accumulation of reactive oxygen species and may play a negative role in induction of apoptosis

21 January 2018

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Upstream and downstream of mTOR

21 January 2018

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Dysregulation of the TSC-mTOR pathway in human disease

21 January 2018

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The TOR pathway: a target for cancer therapy

21 January 2018

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The Akt-mTOR tango and its relevance to cancer

21 January 2018

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Mechanisms of type-I- and type-II-interferon-mediated signalling

21 January 2018

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Tor signalling in bugs, brain and brawn

21 January 2018

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S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

21 January 2018

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Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

21 January 2018

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Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

21 January 2018

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Activation of the p38 mitogen-activated protein kinase by type I interferons

21 January 2018

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Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons

21 January 2018

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Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex

21 January 2018

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The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selection

21 January 2018

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21 January 2018

The two TORCs and Akt.

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mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer

21 January 2018

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Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

21 January 2018

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S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

Map kinase signaling pathways and hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705227200

21 January 2018

Identifiers

DOI

10.1074/JBC.M705227200

1 reference

26 December 2017

1 reference

26 December 2017