(Q46890855)

26 December 2017

title

The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection (English)

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26 December 2017

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4

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26 December 2017

author name string

D Vasilcanu

1

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26 December 2017

W-H Weng

2

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26 December 2017

A Girnita

3

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26 December 2017

R Vasilcanu

5

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26 December 2017

M Axelson

6

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26 December 2017

O Larsson

7

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26 December 2017

C Larsson

8

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26 December 2017

L Girnita

9

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26 December 2017

language of work or name

English

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publication date

1 May 2006

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26 December 2017

published in

Oncogene

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26 December 2017

volume

25

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26 December 2017

issue

22

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26 December 2017

page(s)

3186-3195

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26 December 2017

Structure and function of the type 1 insulin-like growth factor receptor.

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The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript

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Thermal chemistry of podophyllotoxin in ethanol and a comparison of the cytostatic activity of the thermolysis products

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Insulin-like growth factor-I receptor activity is essential for Kaposi's sarcoma growth and survival.

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In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

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Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth.

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Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor

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{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

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A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts

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Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells

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7 January 2021

Tamoxifen-induced cell death in malignant melanoma cells: possible involvement of the insulin-like growth factor-1 (IGF-1) pathway

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7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells

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7 January 2021

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7 January 2021

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7 January 2021

Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of th

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7 January 2021

Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions

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7 January 2021

Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins

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7 January 2021

Imatinib mesylate--gold standards and silver linings

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7 January 2021

An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture

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7 January 2021

Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.

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7 January 2021

Expression and growth dependency of the insulin-like growth factor I receptor in craniopharyngioma cells: a novel therapeutic approach

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7 January 2021

Evidence from monoclonal antibody studies that insulin stimulates deoxyribonucleic acid synthesis through the type I somatomedin receptor

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7 January 2021

The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

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7 January 2021

Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas

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7 January 2021

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7 January 2021

Role of the insulin-like growth factor family in cancer development and progression

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209339

1 reference

26 December 2017

1 reference

26 December 2017