(Q46900150)

English

A signaling mechanism from G alpha q-protein-coupled metabotropic glutamate receptors to gene expression: role of the c-Jun N-terminal kinase pathway.

scientific article published in January 2006

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16421317

A signaling mechanism from G alpha q-protein-coupled metabotropic glutamate receptors to gene expression: role of the c-Jun N-terminal kinase pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

G protein-coupled receptor

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7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

author name string

Lu Yang

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

Limin Mao

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

Hai Chen

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

Michael Catavsan

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

Jonathan Kozinn

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

Anish Arora

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

John Q Wang

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

language of work or name

0 references

publication date

1 January 2006

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16421317

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

26

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

971-980

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen-activated protein kinase signaling cascade in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered interaction between PSD-95 and the NMDA receptor following transient global ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-stimulated activation of DNA synthesis via mitogen-activated protein kinase in primary astrocytes: involvement of protein kinase C and related adhesion focal tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homer: a link between neural activity and glutamate receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group I metabotropic glutamate receptor activation increases phosphorylation of cAMP response element-binding protein, Elk-1, and extracellular signal-regulated kinases in rat dorsal striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinases and cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group I metabotropic glutamate receptors control phosphorylation of CREB, Elk-1 and ERK via a CaMKII-dependent pathway in rat striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Raf/MEK/ERK pathway: new concepts of activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatiotemporal regulation of the p42/p44 MAPK pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate cascade to cAMP response element-binding protein phosphorylation in cultured striatal neurons through calcium-coupled group I metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mixed-lineage kinase control of JNK and p38 MAPK pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group-I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biliverdin reductase, a novel regulator for induction of activating transcription factor-2 and heme oxygenase-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibiting Src family tyrosine kinase activity blocks glutamate signalling to ERK1/2 and Akt/PKB but not JNK in cultured striatal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of MAPK/ERK phosphorylation via ionotropic glutamate receptors in cultured rat striatal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate signaling to Ras-MAPK in striatal neurons: mechanisms for inducible gene expression and plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel Ca2+-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of protein phosphatase 2A in mGluR5-regulated MEK/ERK phosphorylation in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental profile of ErbB receptors in murine central nervous system: implications for functional interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of JNK activation in apoptosis: a double-edged sword

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation sites on the epidermal growth factor receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of AP-1 activity by mitogen-activated protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine kinase inhibition: an approach to drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective interaction of JNK protein kinase isoforms with transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sounding the alarm: protein kinase cascades activated by stress and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology and functions of metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin regulation of mitogen-activated protein kinase kinase (MEK), mitogen-activated protein kinase and casein kinase in the cell nucleus: a possible role in the regulation of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal characteristics of G protein-transactivated EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo expression and regulation of Elk-1, a target of the extracellular-regulated kinase signaling pathway, in the adult rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of mGluR1a-like immunoreactivity and mGluR5-like immunoreactivity in identified populations of striatal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4423-05.2006

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675367&resulttype=core&format=json

11 May 2020

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