(Q47099388)

8 January 2018

title

Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences (English)

1 reference

8 January 2018

Erratum: Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences

0 references

1 reference

whole genome sequencing

1 reference

based on heuristic

inferred from title

corrigendum / erratum

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15

Stephen F Kingsmore

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8 January 2018

author name string

Greyson P Twist

1

1 reference

8 January 2018

Andrea Gaedigk

2

1 reference

8 January 2018

Neil A Miller

3

1 reference

8 January 2018

Emily G Farrow

4

1 reference

8 January 2018

Laurel K Willig

5

1 reference

8 January 2018

Darrell L Dinwiddie

6

1 reference

8 January 2018

Josh E Petrikin

7

1 reference

8 January 2018

Sarah E Soden

8

1 reference

8 January 2018

Suzanne Herd

9

1 reference

8 January 2018

Margaret Gibson

10

1 reference

8 January 2018

Julie A Cakici

11

1 reference

8 January 2018

Amanda K Riffel

12

1 reference

8 January 2018

J Steven Leeder

13

1 reference

8 January 2018

Deendayal Dinakarpandian

14

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8 January 2018

publication date

13 January 2016

1 reference

8 January 2018

published in

NPJ genomic medicine

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8 January 2018

volume

1

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8 January 2018

page(s)

15007

1 reference

8 January 2018

Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.

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CYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele

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Integrating human sequence data sets provides a resource of benchmark SNP and indel genotype calls

23 May 2018

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Challenges in CYP2D6 phenotype assignment from genotype data: a critical assessment and call for standardization

23 May 2018

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Towards the implementation of CYP2D6 and CYP2C19 genotypes in clinical practice: update and report from a pharmacogenetic service clinic

23 May 2018

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Complexities of CYP2D6 gene analysis and interpretation

23 May 2018

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23 May 2018

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Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants

23 May 2018

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23 May 2018

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23 May 2018

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Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants

23 May 2018

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Whole-genome sequencing for optimized patient management

23 May 2018

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Deep sequencing of patient genomes for disease diagnosis: when will it become routine?

23 May 2018

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

23 May 2018

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Pharmacogenetics: from bench to byte--an update of guidelines

23 May 2018

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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

23 May 2018

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Fast and SNP-tolerant detection of complex variants and splicing in short reads

23 May 2018

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Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

23 May 2018

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Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother

23 May 2018

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Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans

23 May 2018

1 reference

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De novo peptide sequencing via tandem mass spectrometry

23 May 2018

1 reference

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The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene

23 May 2018

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Large-scale discovery of novel genetic causes of developmental disorders

23 May 2018

1 reference

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Individualizing the use of medications in children: making Goldilocks happy.

15 August 2018

1 reference

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Effect of CYP2D6, CYP2C9 and ABCB1 genotypes on fluoxetine plasma concentrations and clinical improvement in children and adolescent patients.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

Update on allele nomenclature for human cytochromes P450 and the Human Cytochrome P450 Allele (CYP-allele) Nomenclature Database

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

CYP2D6 update: revised nomenclature for CYP2D7/2D6 hybrid genes

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5685293

Next-generation sequencing of pharmacogenes

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNPJGENMED.2015.7

21 January 2018

Identifiers

DOI

10.1038/NPJGENMED.2015.7

1 reference

8 January 2018

PMC publication ID

5685293

1 reference

8 January 2018

PubMed publication ID

29263805

1 reference

8 January 2018