(Q47612261)

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24 February 2020

title

Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline (English)

1 reference

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24 February 2020

2

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24 February 2020

Soyon Hong

5

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24 February 2020

Jean-Cosme Dodart

10

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24 February 2020

Cynthia A Lemere

13

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24 February 2020

author name string

Qiaoqiao Shi

1

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24 February 2020

Sarah B Matousek

3

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24 February 2020

Katherine Merry

4

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24 February 2020

Jessica E Kenison

6

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24 February 2020

Jeffrey L Frost

7

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24 February 2020

Kevin X Le

8

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24 February 2020

Shaomin Li

9

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24 February 2020

Barbara J Caldarone

11

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24 February 2020

Beth Stevens

12

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24 February 2020

language of work or name

English

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publication date

1 September 2015

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24 February 2020

published in

Journal of Neuroscience

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24 February 2020

volume

35

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24 February 2020

issue

38

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24 February 2020

page(s)

13029-13042

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describes a project that uses

24 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6605437/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Hippocampal neuron and synaptophysin-positive bouton number in aging C57BL/6 mice

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12 December 2020

Temporal accrual of complement proteins in amyloid plaques in Down's syndrome with Alzheimer's disease

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12 December 2020

Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.

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Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early-life stress.

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12 December 2020

Evolution of the lectin-complement pathway and its role in innate immunity

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12 December 2020

Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

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12 December 2020

Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease

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12 December 2020

Postsynaptic signaling and plasticity mechanisms

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12 December 2020

Intranasal immunotherapy for the treatment of Alzheimer's disease: Escherichia coli LT and LT(R192G) as mucosal adjuvants

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12 December 2020

Morphological alterations in the amygdala and hippocampus of mice during ageing.

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12 December 2020

Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum.

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12 December 2020

Understanding contextual fear conditioning: insights from a two-process model

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12 December 2020

Effects of age on immunohistochemical changes in the mouse hippocampus

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12 December 2020

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12 December 2020

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12 December 2020

The significance of the cholinergic system in the brain during aging and in Alzheimer's disease

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12 December 2020

Aging causes partial loss of basal forebrain but no loss of pontine reticular cholinergic neurons

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12 December 2020

The classical complement cascade mediates CNS synapse elimination

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12 December 2020

Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities

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12 December 2020

Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability

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12 December 2020

Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice

1 reference

12 December 2020

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12 December 2020

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12 December 2020

Expression of complement system components during aging and amyloid deposition in APP transgenic mice

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12 December 2020

Chronic stress-induced acceleration of electrophysiologic and morphometric biomarkers of hippocampal aging

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12 December 2020

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12 December 2020

Quantifying synapses: an immunocytochemistry-based assay to quantify synapse number

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12 December 2020

Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors

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12 December 2020

The relationship between age-related hearing loss and synaptic changes in the hippocampus of C57BL/6J mice.

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12 December 2020

Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c

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12 December 2020

Age-associated learning and memory deficits in two mouse versions of the Stone T-maze

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12 December 2020

The ageing cortical synapse: hallmarks and implications for cognitive decline

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12 December 2020

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12 December 2020

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia

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12 December 2020

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner

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12 December 2020

Presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of GluK1 receptors.

1 reference

12 December 2020

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

1 reference

12 December 2020

Hippocampus-dependent place learning enables spatial flexibility in C57BL6/N mice

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12 December 2020

From development to dysfunction: microglia and the complement cascade in CNS homeostasis

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12 December 2020

Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.

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12 December 2020

Unbiased stereological estimation of the number of neurons in the human hippocampus

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12 December 2020

A dramatic increase of C1q protein in the CNS during normal aging.

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12 December 2020

Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3.

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12 December 2020

Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord

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12 December 2020

NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease

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12 December 2020

Neuron numbers and dendritic extent in normal aging and Alzheimer's disease

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12 December 2020

Effect of neonatal handling on age-related impairments associated with the hippocampus

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12 December 2020

Loss of perforated synapses in the dentate gyrus: morphological substrate of memory deficit in aged rats

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12 December 2020

Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging

1 reference

12 December 2020

Brain Aging Correlates: Retardation by Hormonal-Pharmacological Treatments

1 reference

12 December 2020

Hippocampal aging in rats: A morphometric study of multiple variables in semithin sections

1 reference

12 December 2020

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity

1 reference

12 December 2020

Synapse restructuring associated with the maintenance phase of hippocampal long-term potentiation

1 reference

12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

12 December 2020

10.1523/JNEUROSCI.1698-15.2015

Identifiers

DOI

1 reference

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24 February 2020

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24 February 2020

PubMed publication ID

26400934

1 reference