(Q47754380)

5 February 2018

title

Kinetics of amyloid beta-protein degradation determined by novel fluorescence- and fluorescence polarization-based assays. (English)

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5 February 2018

7

Dennis J Selkoe

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5 February 2018

author name string

Malcolm A Leissring

1

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5 February 2018

Alice Lu

2

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5 February 2018

Margaret M Condron

3

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5 February 2018

David B Teplow

4

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5 February 2018

Ross L Stein

5

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5 February 2018

Wesley Farris

6

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5 February 2018

language of work or name

English

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publication date

16 July 2003

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5 February 2018

Journal of Biological Chemistry

published in

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5 February 2018

volume

278

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5 February 2018

issue

39

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5 February 2018

page(s)

37314-37320

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5 February 2018

Clearing the brain's amyloid cobwebs

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M305627200

Metabolic regulation of brain Abeta by neprilysin.

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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

21 January 2018

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Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

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Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

21 January 2018

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Age at onset in two common neurodegenerative diseases is genetically controlled

21 January 2018

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Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample.

21 January 2018

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Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).

21 January 2018

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A sensitive and quantitative assay for measuring cleavage of presenilin substrates

21 January 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

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Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum

21 January 2018

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Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme

21 January 2018

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Fluorescence anisotropy applied to biomolecular interactions.

21 January 2018

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Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

21 January 2018

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Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

21 January 2018

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Proteolytic activation of recombinant pro-memapsin 2 (Pro-beta-secretase) studied with new fluorogenic substrates

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305627200

Neutral endopeptidase can hydrolyze beta-amyloid(1-40) but shows no effect on beta-amyloid precursor protein metabolism

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305627200

Functional human insulin-degrading enzyme can be expressed in bacteria

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305627200

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5 February 2018

PubMed ID

12867419

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5 February 2018