(Q47799650)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Joep de Ligt

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Tom Van Wezel

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Ruben van Boxtel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Francis Blokzijl

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Tomohiro Mizutani

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Nobuo Sasaki

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Valentina Sasselli

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Sam Behjati

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Judith E Grolleman

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Serena Nik-Zainal

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Roland P Kuiper

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Edwin Cuppen

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Hans Clevers

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

14

Hans Clevers

1 reference

14 July 2018

author name string

Francis Blokzijl

3

1 reference

14 July 2018

Tomohiro Mizutani

4

1 reference

14 July 2018

Nobuo Sasaki

5

1 reference

14 July 2018

Valentina Sasselli

6

1 reference

14 July 2018

Sam Behjati

8

1 reference

14 July 2018

Judith E Grolleman

9

1 reference

14 July 2018

Roland P Kuiper

12

1 reference

14 July 2018

Edwin Cuppen

13

1 reference

14 July 2018

language of work or name

English

0 references

publication date

14 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

number of pages

5

1 reference

based on heuristic

inferred from page(s)

published in

Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

volume

358

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

issue

6360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

page(s)

234-238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer

30 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Mutational signatures associated with tobacco smoking in human cancer

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Tissue-specific mutation accumulation in human adult stem cells during life

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Mutational signatures of ionizing radiation in second malignancies

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

DNA repair in species with extreme lifespan differences

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Differential DNA mismatch repair underlies mutation rate variation across the human genome

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Long-term culture of genome-stable bipotent stem cells from adult human liver

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Signatures of mutational processes in human cancer

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Deciphering signatures of mutational processes operative in human cancer

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Base excision repair facilitates a functional relationship between Guanine oxidation and histone demethylation

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Crypt stem cells as the cells-of-origin of intestinal cancer

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

The multifaceted mismatch-repair system

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Deficient DNA mismatch repair: a common etiologic factor for colon cancer

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Sequential cancer mutations in cultured human intestinal stem cells.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Milestones of Lynch syndrome: 1895-2015.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Genome sequencing of normal cells reveals developmental lineages and mutational processes

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Chromatin organization is a major influence on regional mutation rates in human cancer cells.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038908

Prospective derivation of a living organoid biobank of colorectal cancer patients.

14 August 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAO3130

Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAO3130

The Generation of Organoids for Studying Wnt Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAO3130

Fast and accurate short read alignment with Burrows-Wheeler transform

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAO3130

A framework for variation discovery and genotyping using next-generation DNA sequencing data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAO3130

Biallelic NTHL1 Mutations in a Woman with Multiple Primary Tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAO3130

Hereditary colorectal cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28912133

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.AAO3130

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28912133%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

PubMed publication ID

28912133

1 reference