(Q47891380)

6 February 2018

title

Topoisomerase IV catalysis and the mechanism of quinolone action. (English)

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6 February 2018

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3

Osheroff N

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6 February 2018

author name string

Anderson VE

series ordinal

1

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6 February 2018

Gootz TD

series ordinal

2

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6 February 2018

language of work or name

English

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publication date

1 July 1998

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6 February 2018

Journal of Biological Chemistry

published in

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6 February 2018

volume

273

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6 February 2018

issue

28

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6 February 2018

page(s)

17879-17885

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6 February 2018

Biochemical basis for the interactions of type I and type II topoisomerases with DNA.

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DNA gyrase: structure and function.

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When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs

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Structure and function of type II DNA topoisomerases

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DNA gyrase: an enzyme that introduces superhelical turns into DNA

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New topoisomerase essential for chromosome segregation in E. coli.

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Thermosensitive Mutants of E. coli Affected in the Processes of DNA Synthesis and Cellular Division

21 January 2018

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Gene organization in the region containing a new gene involved in chromosome partition in Escherichia coli

21 January 2018

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The role of topoisomerase IV in partitioning bacterial replicons and the structure of catenated intermediates in DNA replication

21 January 2018

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Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro

21 January 2018

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Roles of topoisomerase IV and DNA gyrase in DNA unlinking during replication in Escherichia coli

21 January 2018

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Contrasting enzymatic activities of topoisomerase IV and DNA gyrase from Escherichia coli

21 January 2018

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Topoisomerase IV, not gyrase, decatenates products of site-specific recombination in Escherichia coli

21 January 2018

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Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

21 January 2018

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Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

21 January 2018

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The molecular basis of quinolone action

21 January 2018

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Fluoroquinolone antibacterials: SAR mechanism of action, resistance, and clinical aspects

21 January 2018

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DNA gyrase as a drug target

21 January 2018

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Fluoroquinolone antimicrobial agents

21 January 2018

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Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition

21 January 2018

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Topoisomerase IV is a target of quinolones in Escherichia coli

21 January 2018

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Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase II.

21 January 2018

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Catalytic function of DNA topoisomerase II.

21 January 2018

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Calcium-promoted DNA cleavage by eukaryotic topoisomerase II: trapping the covalent enzyme-DNA complex in an active form.

21 January 2018

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Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones.

21 January 2018

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Mechanism of quinolone action. A drug-induced structural perturbation of the DNA precedes strand cleavage by topoisomerase IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide.

21 January 2018

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Stabilization of the topoisomerase II-DNA cleavage complex by antineoplastic drugs: inhibition of enzyme-mediated DNA religation by 4'-(9-acridinylamino)methanesulfon-m-anisidide.

21 January 2018

1 reference

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Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

21 January 2018

1 reference

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A pyrimido[1,6-a]benzimidazole that enhances DNA cleavage mediated by eukaryotic topoisomerase II: a novel class of topoisomerase II-targeted drugs with cytotoxic potential

21 January 2018

1 reference

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Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fluorescence spectroscopy

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Microbial DNA topoisomerases and their inhibition by antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Drug features that contribute to the activity of quinolones against mammalian topoisomerase II and cultured cells: correlation between enhancement of enzyme-mediated DNA cleavage in vitro and cytotoxic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Defining functional drug-interaction domains on topoisomerase II by exploiting mechanistic differences between drug classes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

A mutation in yeast TOP2 homologous to a quinolone-resistant mutation in bacteria. Mutation of the amino acid homologous to Ser83 of Escherichia coli gyrA alters sensitivity to eukaryotic topoisomerase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.28.17879

21 January 2018

Identifiers

DOI

10.1074/JBC.273.28.17879

1 reference

6 February 2018

PubMed ID

9651393

1 reference

6 February 2018