(Q48003442)

English

Sodium selenate retards epileptogenesis in acquired epilepsy models reversing changes in protein phosphatase 2A and hyperphosphorylated tau.

scientific article published on 11 June 2016

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Sodium selenate retards epileptogenesis in acquired epilepsy models reversing changes in protein phosphatase 2A and hyperphosphorylated tau. (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

object named as

Matthew Hudson

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David K. Wright

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David K Wright

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Christopher M Hovens

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Christopher M Hovens

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Nigel C Jones

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Terence J O'Brien

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Terence J O'Brien

14

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12

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Sandy R Shultz

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Leigh A. Johnston

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object named as

Leigh A Johnston

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Niall M Corcoran

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Niall M Corcoran

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

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Gabi Dezsi

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

author name string

Shi-Jie Liu

1

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Ping Zheng

2

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Emma Braine

5

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Thanh Nguyen

6

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Jamie N Mayo

10

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7 February 2018

http://europepmc.org/abstract/MED/27289302

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publication date

11 June 2016

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

139

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PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Pt 7

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

1919-1938

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

Incidence and predictors of seizures in patients with Alzheimer's disease

1 reference

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21 January 2018

Okadaic acid induces epileptic seizures and hyperphosphorylation of the NR2B subunit of the NMDA receptor in rat hippocampus in vivo

1 reference

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21 January 2018

Pathology and pathophysiology of the amygdala in epileptogenesis and epilepsy

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Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain.

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An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide

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Multinuclear NMR studies on the energy metabolism of glial and neuronal cells

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Z944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling Model

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21 January 2018

Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model

1 reference

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21 January 2018

Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancer.

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21 January 2018

Amyloid-β associated volume loss occurs only in the presence of phospho-tau

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21 January 2018

The time course of acquired epilepsy: implications for therapeutic intervention to suppress epileptogenesis

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21 January 2018

Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)

1 reference

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21 January 2018

Evaluating Alzheimer's disease progression using rate of regional hippocampal atrophy

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21 January 2018

Identification of new epilepsy treatments: issues in preclinical methodology

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21 January 2018

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

1 reference

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21 January 2018

A novel method for fat suppression in RARE sequences

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21 January 2018

Mechanisms of tau-induced neurodegeneration

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Amyloid-β and tau--a toxic pas de deux in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail).

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models

1 reference

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21 January 2018

Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE.

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21 January 2018

Hippocampal T2 signal change during amygdala kindling epileptogenesis.

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21 January 2018

Quantitative diffusion MRI of hippocampus as a surrogate marker for post-traumatic epileptogenesis

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21 January 2018

A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research

1 reference

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21 January 2018

DNA methylation mediates persistent epileptiform activity in vitro and in vivo

1 reference

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21 January 2018

Seizures in Alzheimer's disease: clinicopathologic study.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Kindling and status epilepticus models of epilepsy: rewiring the brain

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Epilepsy and cognitive impairments in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Mechanisms of epileptogenesis and potential treatment targets

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Decreases in HCN mRNA expression in the hippocampus after kindling and status epilepticus in adult rats.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Automatic quantitation of localized in vivo 1H spectra with LCModel.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

Epilepsy, neurodegeneration, and extracellular glutamate in the hippocampus of awake and anesthetized rats treated with okadaic acid

1 reference

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21 January 2018

Pathological tau tangles localize to focal cortical dysplasia in older patients.

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21 January 2018

Serine/threonine phosphatases: mechanism through structure

1 reference

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21 January 2018

Can structural or functional changes following traumatic brain injury in the rat predict epileptic outcome?

1 reference

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21 January 2018

Granulocyte-macrophage colony-stimulating factor is neuroprotective in experimental traumatic brain injury

1 reference

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21 January 2018

Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWW116

21 January 2018

The challenge and promise of anti-epileptic therapy development in animal models

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Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A B(alpha) subunit expression that correlate with enhanced tau phosphorylation

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Spin Diffusion Measurements: Spin Echoes in the Presence of a Time-Dependent Field Gradient

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Neurofibrillary tangle pathology and Braak staging in chronic epilepsy in relation to traumatic brain injury and hippocampal sclerosis: a post-mortem study

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21 January 2018

T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures

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21 January 2018

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

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21 January 2018

Metabolic crisis occurs with seizures and periodic discharges after brain trauma

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21 January 2018

Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation

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Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy.

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21 January 2018

Identifiers

10.1093/BRAIN/AWW116

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/27289302

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