(Q48093547)

8 February 2018

title

Combined loss of PUMA and p21 accelerates c-MYC-driven lymphoma development considerably less than loss of one allele of p53. (English)

1 reference

8 February 2018

author

Liz J Valente

1

1 reference

8 February 2018

Andreas Strasser

4

1 reference

8 February 2018

Stephanie Grabow

object named as

S Grabow

2

0 references

Ana Janic

object named as

A Janic

5

0 references

Cassandra J. Vandenberg

3

object named as

C J Vandenberg

1 reference

8 February 2018

language of work or name

English

0 references

publication date

7 December 2015

1 reference

8 February 2018

published in

Oncogene

1 reference

8 February 2018

volume

35

1 reference

8 February 2018

issue

29

1 reference

8 February 2018

page(s)

3866-3871

1 reference

8 February 2018

Cancer. p53, guardian of the genome

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

p53 in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Tumor suppression by Ink4a-Arf: progress and puzzles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

The role of p21(waf1/cip1) and p27(Kip1) in HDACi-mediated tumor cell death and cell cycle arrest in the Eμ-myc model of B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

p21 delays tumor onset by preservation of chromosomal stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Apoptotic signaling by c-MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Deconstructing p53 transcriptional networks in tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Transcriptional control of human p53-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FONC.2015.457

21 January 2018

12 December 2020

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

2 references

https://api.crossref.org/works/10.1038%2FONC.2015.457

21 January 2018

12 December 2020

p21WAF1 Mutation Is Not a Predominant Alteration in Pediatric Bone Tumors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.457

Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal

31 March 2020

1 reference

12 December 2020

Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties

1 reference

12 December 2020

Absence of WAF1 mutations in a variety of human malignancies

1 reference

12 December 2020

Progenitor tumours from Emu-bcl-2-myc transgenic mice have lymphomyeloid differentiation potential and reveal developmental differences in cell survival

1 reference

12 December 2020

Tumor susceptibility of p21(Waf1/Cip1)-deficient mice.

1 reference

12 December 2020

Altered WAF1 genes do not play a role in abnormal cell cycle regulation in breast cancers lacking p53 mutations.

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2015.457

1 reference

8 February 2018

1 reference

8 February 2018