(Q48116098)

8 February 2018

title

Inhibition of amyloid-β plaque formation by α-synuclein (English)

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8 February 2018

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Melanie Meyer-Luehmann

15

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8 February 2018

Christian Haass

14

object named as

Christian Haass

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ALBERTO SERRANO-POZO

object named as

Alberto Serrano-Pozo

9

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Bradley Hyman

13

object named as

Bradley T Hyman

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8 February 2018

11

Marco Prinz

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8 February 2018

author name string

Teresa Bachhuber

1

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8 February 2018

Natalie Katzmarski

2

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8 February 2018

Joanna F McCarter

3

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8 February 2018

Desiree Loreth

4

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8 February 2018

Sabina Tahirovic

5

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8 February 2018

Frits Kamp

6

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8 February 2018

Claudia Abou-Ajram

7

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8 February 2018

Brigitte Nuscher

8

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8 February 2018

Alexandra Müller

10

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8 February 2018

Harald Steiner

12

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8 February 2018

language of work or name

English

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publication date

22 June 2015

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8 February 2018

published in

Nature Medicine

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8 February 2018

volume

21

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8 February 2018

issue

7

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8 February 2018

page(s)

802-807

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8 February 2018

Dementia with Lewy bodies

cites work

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Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

21 January 2018

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Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC

21 January 2018

1 reference

Residues in the synuclein consensus motif of the α-synuclein fragment, NAC, participate in transglutaminase-catalysed cross-linking to Alzheimer-disease amyloid βA4 peptide

21 January 2018

1 reference

Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases

21 January 2018

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Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

21 January 2018

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The many faces of α-synuclein: from structure and toxicity to therapeutic target

21 January 2018

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Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

21 January 2018

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Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

21 January 2018

1 reference

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

21 January 2018

1 reference

Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

21 January 2018

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Induction of intracellular tau aggregation is promoted by α-synuclein seeds and provides novel insights into the hyperphosphorylation of tau.

21 January 2018

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Distinct α-synuclein strains differentially promote tau inclusions in neurons

21 January 2018

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Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

21 January 2018

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Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

21 January 2018

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Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

21 January 2018

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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

21 January 2018

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

21 January 2018

1 reference

Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer's disease

21 January 2018

1 reference

Comparison of Lewy body variant of Alzheimer's disease with pure Alzheimer's disease: Consortium to Establish a Registry for Alzheimer's Disease, Part XIX.

21 January 2018

1 reference

Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study

21 January 2018

1 reference

Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease

21 January 2018

1 reference

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

21 January 2018

1 reference

Extracellular amyloid formation and associated pathology in neural grafts

21 January 2018

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Neocortical synapse density and Braak stage in the Lewy body variant of Alzheimer disease: a comparison with classic Alzheimer disease and normal aging

21 January 2018

1 reference

Frontal cortical synaptophysin in Lewy body diseases: relation to Alzheimer's disease and dementia

21 January 2018

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Cognitive decline is faster in Lewy body variant than in Alzheimer's disease

21 January 2018

1 reference

CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia

21 January 2018

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The amyloid state of proteins in human diseases

21 January 2018

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The GxGD motif of presenilin contributes to catalytic function and substrate identification of gamma-secretase.

21 January 2018

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Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease

21 January 2018

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Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments.

21 January 2018

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Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

21 January 2018

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12 December 2020

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

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12 December 2020

The more cortical amyloid-β, the more postural instability in Parkinson's disease: more grist to the mill for a link between walking, falling, and remembering?

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12 December 2020

Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein

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12 December 2020

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

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12 December 2020

Dementia with Lewy bodies versus pure Alzheimer disease: differences in cognition, neuropathology, cholinergic dysfunction, and synapse density.

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12 December 2020

alpha-Synuclein is phosphorylated in synucleinopathy lesions

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12 December 2020

Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry.

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12 December 2020

Evidence for seeding of beta -amyloid by intracerebral infusion of Alzheimer brain extracts in beta -amyloid precursor protein-transgenic mice.

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12 December 2020

Identifiers

DOI

10.1038/NM.3885

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8 February 2018

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8 February 2018