(Q51843744)

13 April 2018

http://europepmc.org/abstract/MED/23238734

title

Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments. (English)

1 reference

13 April 2018

http://europepmc.org/abstract/MED/23238734

author

Peer-Hendrik Kuhn

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

Orly Reiner

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

Stefan F Lichtenthaler

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

author name string

Richard M Page

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

Anna Münch

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

Thomas Horn

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

Alessio Colombo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

Michael Boutros

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

Harald Steiner

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

Christian Haass

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 December 2012

1 reference

13 April 2018

http://europepmc.org/abstract/MED/23238734

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

issue

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

page(s)

18204-18214

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

A novel substrate for analyzing Alzheimer's disease gamma-secretase

15 May 2020

cites work

1 reference

12 December 2020

Comparative genomics of the eukaryotes

1 reference

12 December 2020

Homologs of the alpha- and beta-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome

1 reference

12 December 2020

Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases

1 reference

12 December 2020

Platelet-activating factor acetylhydrolase (PAF-AH).

1 reference

12 December 2020

Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation

1 reference

12 December 2020

Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1.

1 reference

12 December 2020

Targeted disruption of intracellular type I platelet activating factor-acetylhydrolase catalytic subunits causes severe impairment in spermatogenesis

1 reference

12 December 2020

Reconstitution of gamma-secretase activity

1 reference

12 December 2020

Previously uncharacterized roles of platelet-activating factor acetylhydrolase 1b complex in mouse spermatogenesis

1 reference

12 December 2020

The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase

1 reference

12 December 2020

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

12 December 2020

Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.

1 reference

12 December 2020

Genome-wide RNAi analysis of growth and viability in Drosophila cells

1 reference

12 December 2020

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

1 reference

12 December 2020

Cytoplasmic tail adaptors of Alzheimer's amyloid-beta protein precursor

1 reference

12 December 2020

Coupling PAF Signaling to Dynein Regulation

1 reference

12 December 2020

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

12 December 2020

Analysis of cell-based RNAi screens.

1 reference

12 December 2020

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

1 reference

12 December 2020

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

12 December 2020

The Pafah1b complex interacts with the reelin receptor VLDLR

1 reference

12 December 2020

The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.

1 reference

12 December 2020

Generation of Abeta38 and Abeta42 is independently and differentially affected by familial Alzheimer disease-associated presenilin mutations and gamma-secretase modulation

1 reference

12 December 2020

The art and design of genetic screens: RNA interference.

1 reference

12 December 2020

Amyloid precursor protein trafficking, processing, and function

1 reference

12 December 2020

Intramembrane proteolysis by gamma-secretase

1 reference

12 December 2020

Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function

1 reference

12 December 2020

The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons

1 reference

12 December 2020

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

1 reference

12 December 2020

Beta-amyloid precursor protein mutants respond to gamma-secretase modulators

1 reference

12 December 2020

Rapid and direct transport of cell surface APP to the lysosome defines a novel selective pathway

1 reference

12 December 2020

Alzheimer's disease: strategies for disease modification

1 reference

12 December 2020

Reduction of brain beta-amyloid (Abeta) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, through increase in degradation of amyloid precursor protein C-terminal fragments (APP-CTFs) and Abeta clearance

1 reference

12 December 2020

Design and evaluation of genome-wide libraries for RNA interference screens

1 reference

12 December 2020

ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons

1 reference

12 December 2020

PAF-AH Catalytic Subunits Modulate the Wnt Pathway in Developing GABAergic Neurons

1 reference

12 December 2020

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease

1 reference

12 December 2020

α-secretase in Alzheimer's disease: molecular identity, regulation and therapeutic potential

1 reference

12 December 2020

The phospholipase A₂ enzyme complex PAFAH Ib mediates endosomal membrane tubule formation and trafficking

1 reference

12 December 2020

Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines

1 reference

12 December 2020

A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid)

1 reference

12 December 2020

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

1 reference

12 December 2020

Purification and characterization of bovine brain platelet-activating factor acetylhydrolase

1 reference

12 December 2020

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

1 reference

12 December 2020

The role of APP processing and trafficking pathways in the formation of amyloid beta-protein

1 reference

12 December 2020

KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis

1 reference

12 December 2020

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1 reference

12 December 2020

Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

1 reference

12 December 2020

Coupling PAF signaling to dynein regulation: structure of LIS1 in complex with PAF-acetylhydrolase

1 reference

12 December 2020

10.1523/JNEUROSCI.2681-12.2012

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621731&resulttype=core&format=json

15 May 2020

1 reference