(Q48221527)

9 February 2018

title

The regulation of p53 up-regulated modulator of apoptosis by JNK/c-Jun pathway in β-amyloid-induced neuron death (English)

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9 February 2018

author name string

Rumana Akhter

1

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9 February 2018

Priyankar Sanphui

2

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9 February 2018

Hrishita Das

3

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9 February 2018

Pampa Saha

4

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9 February 2018

Subhas Chandra Biswas

5

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9 February 2018

language of work or name

English

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publication date

17 April 2015

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9 February 2018

Journal of Neurochemistry

published in

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9 February 2018

volume

134

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issue

6

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page(s)

1091-1103

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9 February 2018

The essential role of p53-up-regulated modulator of apoptosis (Puma) and its regulation by FoxO3a transcription factor in β-amyloid-induced neuron death

cites work

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The JNK- and AKT/GSK3β- signaling pathways converge to regulate Puma induction and neuronal apoptosis induced by trophic factor deprivation

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Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

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Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

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JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents

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The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway.

21 January 2018

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Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

21 January 2018

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Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.

21 January 2018

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Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.

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JNK signalling: a possible target to prevent neurodegeneration.

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JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis

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Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons.

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Ischemia activates JNK/c-Jun/AP-1 pathway to up-regulate 14-3-3gamma in astrocyte.

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Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

21 January 2018

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TRAIL death receptors DR4 and DR5 mediate cerebral microvascular endothelial cell apoptosis induced by oligomeric Alzheimer's Aβ.

21 January 2018

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CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

21 January 2018

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The role of amyloid β in the pathogenesis of Alzheimer's disease

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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Amyloid, the presenilins and Alzheimer's disease

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Alzheimer mechanisms and therapeutic strategies

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

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Targeting the JNK signaling pathway for stroke and Parkinson's diseases therapy

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A critical role of neural-specific JNK3 for ischemic apoptosis

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Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicity

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Brain amyloid-β oligomers in ageing and Alzheimer's disease

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Quantitative neuronal c-fos and c-jun expression in Alzheimer's disease

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Neurotoxicity of amyloid β-protein: synaptic and network dysfunction

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The JNK/c-Jun cascade and Alzheimer's disease

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The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia

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c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

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Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

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Activated c-Jun is present in neurofibrillary tangles in Alzheimer's disease brains.

21 January 2018

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The role of c-Jun N-terminal kinase (JNK) in Parkinson's disease.

21 January 2018

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BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program

21 January 2018

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FoxO3a is activated and executes neuron death via Bim in response to β-amyloid

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c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo.

21 January 2018

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

21 January 2018

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Activation of JNK signaling mediates amyloid-ß-dependent cell death

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c-Jun phosphorylation in Alzheimer disease

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beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

21 January 2018

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Regulation of caspases in the nervous system implications for functions in health and disease

21 January 2018

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Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor.

21 January 2018

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Early activation of the Kaposi's sarcoma-associated herpesvirus RTA, RAP, and MTA promoters by the tetradecanoyl phorbol acetate-induced AP1 pathway.

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

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Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

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FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

21 January 2018

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The BCL-2 protein family: opposing activities that mediate cell death

21 January 2018

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PUMA, a potent killer with or without p53

21 January 2018

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JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells

21 January 2018

1 reference

Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JNC.13128

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9 February 2018

release_7bacby5bwjem5dvbqzohjyp5ai

Fatcat ID

0 references

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9 February 2018