(Q48230762)

http://europepmc.org/abstract/MED/28985763

9 February 2018

title

Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

Ervin Welker

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

author name string

András Tálas

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

Krisztina Huszár

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

Zoltán Ligeti

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

Eszter Tóth

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

Nóra Weinhardt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

Elfrieda Fodor

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

publication date

6 October 2017

1 reference

http://europepmc.org/abstract/MED/28985763

9 February 2018

published in

Genome Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

page(s)

190

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

describes a project that uses

13 May 2020

ggplot2

object named as

ggplot2

2 references

10 June 2022

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=6389135

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

dplyr

object named as

dplyr

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

exact match

https://scigraph.springernature.com/pub.10.1186/s13059-017-1318-8

0 references

cites work

CRISPR-Cas systems for editing, regulating and targeting genomes

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Development and applications of CRISPR-Cas9 for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

RNA-programmed genome editing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

RNA-guided human genome engineering via Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

DNA targeting specificity of RNA-guided Cas9 nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

A split-Cas9 architecture for inducible genome editing and transcription modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Small molecule-triggered Cas9 protein with improved genome-editing specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Engineered CRISPR-Cas9 nucleases with altered PAM specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Rationally engineered Cas9 nucleases with improved specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Cpf1 nucleases demonstrate robust activity to induce DNA modification by exploiting homology directed repair pathways in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Easy quantitative assessment of genome editing by sequence trace decomposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

The transcriptional start site for a human U6 small nuclear RNA gene is dictated by a compound promoter element consisting of the PSE and the TATA box

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

FLASH assembly of TALENs for high-throughput genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Ribozyme Mediated gRNA Generation for In Vitro and In Vivo CRISPR/Cas9 Mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Highly efficient Cas9-mediated transcriptional programming

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

CRISPR RNA-guided activation of endogenous human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Comparison of Cas9 activators in multiple species

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Cas9 gRNA engineering for genome editing, activation and repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Inducible in vivo genome editing with CRISPR-Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Photoactivatable CRISPR-Cas9 for optogenetic genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

A chemical-inducible CRISPR-Cas9 system for rapid control of genome editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Rational design of a split-Cas9 enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Positive and negative regulation of endogenous genes by designed transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

A one pot, one step, precision cloning method with high throughput capability

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Cloning Should Be Simple: Escherichia coli DH5α-Mediated Assembly of Multiple DNA Fragments with Short End Homologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

Restriction enzyme body doubles and PCR cloning: on the general use of type IIs restriction enzymes for cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-mediated integration of a 'self-cleaving' GFP-expression plasmid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

BoxPlotR: a web tool for generation of box plots

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-017-1318-8

10.1186/S13059-017-1318-8

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

Dimensions Publication ID

13 May 2020

1092114906

0 references

Fatcat ID

release_f4tfmafcwrctnf4op4unzqxj3m

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6389135&resulttype=core&format=json

13 May 2020

1 reference