(Q48467687)

English

Cholinergic Basal Forebrain Lesion Decreases Neurotrophin Signaling without Affecting Tau Hyperphosphorylation in Genetically Susceptible Mice.

scientific article published on 20 October 2016

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scholarly article

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/27767994

Cholinergic Basal Forebrain Lesion Decreases Neurotrophin Signaling without Affecting Tau Hyperphosphorylation in Genetically Susceptible Mice. (English)

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/27767994

Marion T Turnbull

object named as

Marion T Turnbull

1

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Elizabeth J. Coulson

object named as

Elizabeth J Coulson

2

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publication date

20 October 2016

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/27767994

Journal of Alzheimer's Disease

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/27767994

55

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/27767994

3

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/27767994

1141-1154

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/27767994

Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Atrophy of the cholinergic Basal forebrain over the adult age range and in early stages of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

The cholinergic deficit coincides with Abeta deposition at the earliest histopathologic stages of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Basal forebrain atrophy correlates with amyloid β burden in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Cholinergic basal forebrain atrophy predicts amyloid burden in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

The history of the cholinergic hypothesis

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

The cholinergic lesion of Alzheimer's disease: pivotal factor or side show?

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Divergent phosphorylation pattern of tau in P301L tau transgenic mice.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Tau filament formation in transgenic mice expressing P301L tau.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Tau aggregation and its interplay with amyloid-β.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Immunolesion-induced loss of cholinergic projection neurones promotes β-amyloidosis and tau hyperphosphorylation in the hippocampus of triple-transgenic mice

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Endogenous Aβ causes cell death via early tau hyperphosphorylation.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Selective loss of basal forebrain cholinergic neurons by 192 IgG-saporin is associated with decreased phosphorylation of Ser glycogen synthase kinase-3beta.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

The role of p75NTR in cholinergic basal forebrain structure and function.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Septal cholinergic afferents regulate expression of brain-derived neurotrophic factor and beta-nerve growth factor mRNA in rat hippocampus

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: evidence from lesion and chronic cholinergic drug treatment studies

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Effects of cholinergic denervation on seizure development and neurotrophin messenger RNA regulation in rapid hippocampal kindling

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Immunolesioning of basal forebrain cholinergic neurons facilitates hippocampal kindling and perturbs neurotrophin messenger RNA regulation

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Selective immunotoxic lesions of basal forebrain cholinergic cells: effects on learning and memory in rats

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Intact spatial learning and memory in transgenic mice with reduced BDNF.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Impaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Reduction of basal forebrain cholinergic system parallels cognitive impairment in patients at high risk of developing Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160805

21 January 2018

Identifiers

10.3233/JAD-160805

0 references

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/27767994

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