(Q48598406)

13 February 2018

title

Pharmacokinetic consequences of active drug efflux at the blood-brain barrier (English)

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13 February 2018

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1

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13 February 2018

author name string

Rujia Xie

series ordinal

2

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13 February 2018

Selma Sahin

series ordinal

3

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13 February 2018

Margareta Hammarlund-Udenaes

series ordinal

4

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13 February 2018

publication date

7 April 2006

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13 February 2018

published in

Pharmaceutical Research

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13 February 2018

volume

23

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13 February 2018

issue

4

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13 February 2018

page(s)

705-717

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13 February 2018

Cerebral glucose transport and oxygen consumption in sheep and rabbits

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https://api.crossref.org/works/10.1007%2FS11095-006-9780-0

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21 January 2018

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Regional blood-brain glucose transfer in the rat: a novel double-membrane kinetic analysis

21 January 2018

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Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum

21 January 2018

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Modelling of the blood-brain barrier transport of morphine-3-glucuronide studied using microdialysis in the rat: involvement of probenecid-sensitive transport

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-006-9780-0

Efflux transport of tolbutamide across the blood-brain barrier

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-006-9780-0

Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier

21 January 2018

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12 December 2020

Rationale for influx enhancement versus efflux blockade to increase drug exposure to the brain

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12 December 2020

Blood-brain barrier transport and brain distribution of morphine-6-glucuronide in relation to the antinociceptive effect in rats--pharmacokinetic/pharmacodynamic modelling

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12 December 2020

The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach.

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12 December 2020

Kinetic analysis of the mechanism of action of the multidrug transporter.

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12 December 2020

The ATP switch model for ABC transporters

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12 December 2020

Kinetics of the multidrug transporter (P-glycoprotein) and its reversal

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12 December 2020

Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates.

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12 December 2020

The use of microdialysis in CNS drug delivery studies. Pharmacokinetic perspectives and results with analgesics and antiepileptics

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12 December 2020

Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain.

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12 December 2020

Physiological parameters in laboratory animals and humans

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12 December 2020

Morphine blood-brain barrier transport is influenced by probenecid co-administration

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12 December 2020

Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells.

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12 December 2020

Is the multidrug transporter a flippase?

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12 December 2020

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

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12 December 2020

Drainage of interstitial fluid from different regions of rat brain

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12 December 2020

Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier

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12 December 2020

Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood and brain.

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12 December 2020

Computer simulation of the blood-brain barrier: a model including two membranes, blood flow, facilitated and non-facilitated diffusion

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12 December 2020

Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs

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12 December 2020

Hydroxyurea transport across the blood-brain and blood-cerebrospinal fluid barriers of the guinea-pig

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12 December 2020

Influence of probenecid on the delivery of morphine-6-glucuronide to the brain

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12 December 2020

Interdependent effect of P-glycoprotein-mediated drug efflux and intracellular drug binding on intracellular paclitaxel pharmacokinetics: application of computational modeling

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12 December 2020

In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier

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12 December 2020

Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells

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12 December 2020

Log(BB), PS products and in silico models of drug brain penetration

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12 December 2020

Theoretical aspects of P-glycoprotein mediated drug efflux on the distribution volume of anaesthetic-related drugs in the brain.

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12 December 2020

Variable modulation of opioid brain uptake by P-glycoprotein in mice

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12 December 2020

The P-glycoprotein efflux pump: how does it transport drugs?

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12 December 2020

Fluorescent cellular indicators are extruded by the multidrug resistance protein.

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12 December 2020

10.1007/S11095-006-9780-0

Identifiers

DOI

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13 February 2018

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13 February 2018