(Q48769009)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26198811%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

HDAC6 and RhoA are novel players in Abeta-driven disruption of neuronal polarity (English)

1 reference

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20 February 2020

5

1 reference

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20 February 2020

Francesco Difato

7

1 reference

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20 February 2020

Hanako Tsushima

1

1 reference

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20 February 2020

Evelina Chieregatti

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26198811%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Marco Emanuele

2

1 reference

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20 February 2020

Alice Polenghi

3

1 reference

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20 February 2020

Alessandro Esposito

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26198811%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Andrea Barberis

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26198811%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

language of work or name

English

0 references

publication date

22 July 2015

1 reference

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20 February 2020

published in

Nature Communications

1 reference

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20 February 2020

volume

6

1 reference

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20 February 2020

page(s)

7781

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https://scigraph.springernature.com/pub.10.1038/ncomms8781

20 February 2020

exact match

0 references

cites work

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Tau is essential to beta -amyloid-induced neurotoxicity

21 January 2018

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Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

21 January 2018

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Tau reduction prevents Abeta-induced defects in axonal transport.

21 January 2018

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Aβ Oligomers Cause Localized Ca2+Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

21 January 2018

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Linking amyloid-β and tau: amyloid-β induced synaptic dysfunction via local wreckage of the neuronal cytoskeleton.

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

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Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

21 January 2018

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The acetylation of tau inhibits its function and promotes pathological tau aggregation

21 January 2018

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Acetylation of tau inhibits its degradation and contributes to tauopathy

21 January 2018

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HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions

21 January 2018

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HDAC6 is a microtubule-associated deacetylase

21 January 2018

1 reference

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Impaired function of HDAC6 slows down axonal growth and interferes with axon initial segment development

21 January 2018

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End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment

21 January 2018

1 reference

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Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

21 January 2018

1 reference

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Long-range and long-term interferometric tracking by static and dynamic force-clamp optical tweezers

21 January 2018

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Cell signaling experiments driven by optical manipulation

21 January 2018

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Polymerizing actin fibers position integrins primed to probe for adhesion sites

21 January 2018

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Non-muscle myosin II takes centre stage in cell adhesion and migration

21 January 2018

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Activity of Rho-family GTPases during cell division as visualized with FRET-based probes

21 January 2018

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mDia mediates Rho-regulated formation and orientation of stable microtubules

21 January 2018

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Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

21 January 2018

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Regulation of microtubule dynamics in 3T3 fibroblasts by Rho family GTPases

21 January 2018

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The acetylation of alpha-tubulin and its relationship to the assembly and disassembly of microtubules

21 January 2018

1 reference

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In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

21 January 2018

1 reference

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Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells

21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

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Spatiotemporal dynamics of RhoA activity in migrating cells

21 January 2018

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The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease.

21 January 2018

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Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth cones

21 January 2018

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Dynamic instability of microtubules is regulated by force

21 January 2018

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Tau--an inhibitor of deacetylase HDAC6 function

21 January 2018

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Multiple roles of HDAC inhibition in neurodegenerative conditions.

21 January 2018

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Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition.

21 January 2018

1 reference

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Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

21 January 2018

1 reference

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HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

21 January 2018

1 reference

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Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

21 January 2018

1 reference

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Hdac6 knock-out increases tubulin acetylation but does not modify disease progression in the R6/2 mouse model of Huntington's disease

21 January 2018

1 reference

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Protein kinase CK2 regulates the formation and clearance of aggresomes in response to stress

21 January 2018

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HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

21 January 2018

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

21 January 2018

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Drosophila histone deacetylase 6 protects dopaminergic neurons against {alpha}-synuclein toxicity by promoting inclusion formation

21 January 2018

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Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

21 January 2018

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TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

21 January 2018

1 reference

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Histone deacetylase 6 interacts with the microtubule-associated protein tau

21 January 2018

1 reference

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Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

21 January 2018

1 reference

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HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes

21 January 2018

1 reference

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Tau mutants bind tubulin heterodimers with enhanced affinity

21 January 2018

1 reference

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The role of local actin instability in axon formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

Microtubule stabilization specifies initial neuronal polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

Actin turnover is required to prevent axon retraction driven by endogenous actomyosin contractility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

Selective filtering defect at the axon initial segment in Alzheimer's disease mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

Motility flow and growth-cone navigation analysis during in vitro neuronal development by long-term bright-field imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

Force generation in lamellipodia is a probabilistic process with fast growth and retraction events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8781

Reduction of acetylated alpha-tubulin immunoreactivity in neurofibrillary tangle-bearing neurons in Alzheimer's disease.

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FNCOMMS8781

21 January 2018

12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

The beta-amyloid protein of Alzheimer's disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism

1 reference

12 December 2020

The role of synaptic proteins in Alzheimer's disease

1 reference

12 December 2020

Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation

1 reference

12 December 2020

Increase in neurite outgrowth mediated by overexpression of actin depolymerizing factor.

1 reference

12 December 2020

Increased microtubule stability and alpha tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or tau

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS8781

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26198811%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

ADS bibcode

2015NatCo...6.7781T

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26198811%20AND%20SRC:MED&resulttype=core&format=json