(Q48769729)

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Mitochondrial Dysfunction Triggers Synaptic Deficits via Activation of p38 MAP Kinase Signaling in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells.

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scholarly article

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Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Mitochondrial Dysfunction Triggers Synaptic Deficits via Activation of p38 MAP Kinase Signaling in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells. (English)

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Alzheimer's disease

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author name string

Qing Yu

1

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Fang Du

2

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Justin T Douglas

3

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Haiyang Yu

4

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Shirley ShiDu Yan

5

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Shi Fang Yan

6

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

publication date

1 January 2017

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Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Journal of Alzheimer's Disease

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Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

59

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

1

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

223-239

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

Antioxidants Rescue Mitochondrial Transport in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells

1 reference

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1 reference

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Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines

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1 reference

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1 reference

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Prodromal metabolic phenotype in MCI cybrids: implications for Alzheimer's disease.

1 reference

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Synaptic changes in Alzheimer's disease and its models

1 reference

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Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease

1 reference

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1 reference

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1 reference

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1 reference

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Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease

1 reference

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1 reference

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Early calcium dysregulation in Alzheimer's disease: setting the stage for synaptic dysfunction

1 reference

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1 reference

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The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

1 reference

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Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease

1 reference

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Effects of synaptic modulation on beta-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice.

1 reference

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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

1 reference

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Puerarin protects Alzheimer's disease neuronal cybrids from oxidant-stress induced apoptosis by inhibiting pro-death signaling pathways

1 reference

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Amyloid-β as a modulator of synaptic plasticity

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Microglial receptor for advanced glycation end product-dependent signal pathway drives beta-amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex

1 reference

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MAPK, beta-amyloid and synaptic dysfunction: the role of RAGE.

1 reference

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10 July 2018

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

1 reference

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Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy

1 reference

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Synaptic degeneration in Alzheimer's disease

1 reference

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Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model

1 reference

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Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells

1 reference

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10 July 2018

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

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beta-Adrenoceptor blockers protect against staurosporine-induced apoptosis in SH-SY5Y neuroblastoma cells

1 reference

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Endophilin I expression is increased in the brains of Alzheimer disease patients

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Neuronal differentiation and long-term culture of the human neuroblastoma line SH-SY5Y.

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Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies

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Mitochondria and neuronal activity.

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Apoptosis mediated by p53 in rat neural AF5 cells following treatment with hydrogen peroxide and staurosporine

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Molecular mechanisms of dendritic spine morphogenesis

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Differentiated Alzheimer's disease transmitochondrial cybrid cell lines exhibit reduced organelle movement

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The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

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Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence

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RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice

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Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

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10 July 2018

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10 July 2018

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10 July 2018

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

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10 July 2018

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Creation and characterization of mitochondrial DNA-depleted cell lines with "neuronal-like" properties.

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Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

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NeuN, a neuronal specific nuclear protein in vertebrates

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14 August 2018

Oxidative stress-induced formation of a positive-feedback loop for the sustained activation of p38 MAPK leading to the loss of cell division in cardiomyocytes soon after birth.

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14 August 2018

Reduction in post-synaptic scaffolding PSD-95 and SAP-102 protein levels in the Alzheimer inferior temporal cortex is correlated with disease pathology

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14 August 2018

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

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14 August 2018

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

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14 August 2018

Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes

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14 August 2018

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14 August 2018

Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5935489

14 August 2018

Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5935489

14 August 2018

Identifiers

10.3233/JAD-170283

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5935489

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