(Q48832254)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

0 references

0 references

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Javier Vitorica

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Ana M. Fernandez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Ignacio Torres Aleman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

M Mecha

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

D Dávila

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

C Guaza

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

language of work or name

English

0 references

publication date

18 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

705-718

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

Serum insulin-like growth factor I regulates brain amyloid-beta levels

14 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Reduced IGF-1 signaling delays age-associated proteotoxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Inflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Reimagining Alzheimer's disease--an age-based hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Clearing the brain's amyloid cobwebs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Attenuation of scopolamine-induced impairment of spontaneous alteration behaviour by antagonist but not inverse agonist and agonist beta-carbolines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Insulin-like growth factor-I-forkhead box O transcription factor 3a counteracts high glucose/tumor necrosis factor-α-mediated neuronal damage: implications for human immunodeficiency virus encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Phosphatases at the heart of FoxO metabolic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Combinatorial roles of nuclear receptors in inflammation and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Mechanisms underlying inflammation in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Rapid appearance of beta-amyloid precursor protein immunoreactivity in damaged axons and reactive glial cells in rat brain following needle stab injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Oxidative stress, glutamate, and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Up-regulation of calcineurin Abeta mRNA in the Alzheimer's disease brain: assessment by cDNA microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Selective changes of calcineurin (protein phosphatase 2B) activity in Alzheimer's disease cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Rosiglitazone Monotherapy in Mild-to-Moderate Alzheimer’s Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase III Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Developmental regulation of the mouse IGF-I exon 1 promoter region by calcineurin activation of NFAT in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

A critical role for IGF-II in memory consolidation and enhancement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

IGF-1-induced processing of the amyloid precursor protein family is mediated by different signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

Insulin-like growth factor-I stimulates dephosphorylation of ikappa B through the serine phosphatase calcineurin (protein phosphatase 2B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

7 January 2021

Patients with Alzheimer's disease display a pro-inflammatory phenotype

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

7 January 2021

Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

7 January 2021

Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

7 January 2021

[Functional roles of constitutively active calcineurin in delayed neuronal death after brain ischemia]

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.128

7 January 2021

Identifiers

DOI

10.1038/MP.2011.128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005929%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference