(Q48957718)

17 February 2018

title

Multiple cellular and molecular mechanisms are involved in human Aβ clearance by transplanted adult astrocytes (English)

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17 February 2018

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Rea Pihlaja

1

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17 February 2018

Jari Koistinaho

2

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17 February 2018

Riitta Kauppinen

3

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17 February 2018

Jouko Sandholm

4

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17 February 2018

Heikki Tanila

5

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17 February 2018

Milla Koistinaho

6

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17 February 2018

publication date

8 August 2011

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17 February 2018

published in

Glia

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17 February 2018

volume

59

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17 February 2018

issue

11

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17 February 2018

page(s)

1643-1657

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17 February 2018

Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.

cites work

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Inflammation and Alzheimer's disease

21 January 2018

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1002%2FGLIA.21212

A guided tour into subcellular colocalization analysis in light microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Angiotensin converting enzyme in the human basal forebrain and midbrain visualized by in vitro autoradiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Cellular Expression of Isoforms of Endothelin-Converting Enzyme-1 (ECE-1c, ECE-1b and ECE-1a) and Endothelin-Converting Enzyme-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Metabolic regulation of brain Abeta by neprilysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Human neprilysin is capable of degrading amyloid beta peptide not only in the monomeric form but also the pathological oligomeric form

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Specific uptake of Aβ1-40 in rat brain occurs in astrocyte, but not in microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Binding and uptake of A beta1-42 by primary human astrocytes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

'Green mice' as a source of ubiquitous green cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Proteolysis of A beta peptide from Alzheimer disease brain by gelatinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Syngeneic central nervous system transplantation of genetically transduced mature, adult astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Folding proteins in fatal ways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Astrocyte apoptosis: implications for neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Molecular pharmacology of endothelin converting enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Adult mouse astrocytes degrade amyloid-beta in vitro and in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Phospholipases A2 mediate amyloid-beta peptide-induced mitochondrial dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

7 January 2021

Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

7 January 2021

Degradation of Alzheimer's beta-amyloid protein by human cathepsin D.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

7 January 2021

Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

7 January 2021

Amyloid-beta 1-42 induced endocytosis and clusterin/apoJ protein accumulation in cultured human astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

7 January 2021

Chemokine expression by astrocytes plays a role in microglia/macrophage activation and subsequent neurodegeneration in secondary progressive multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

7 January 2021

The plasmin system is induced by and degrades amyloid-beta aggregates

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

7 January 2021

Angiotensin-converting enzyme converts amyloid beta-protein 1-42 (Abeta(1-42)) to Abeta(1-40), and its inhibition enhances brain Abeta deposition

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21212

7 January 2021

Identifiers

DOI

10.1002/GLIA.21212

1 reference

17 February 2018

1 reference

17 February 2018