(Q50435350)

English

Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.

scientific article published on 9 June 2017

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600358%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock (English)

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22 March 2020

G protein-coupled receptor

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Jean-Philippe Gratton

6

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22 March 2020

Jose Vazquez-prado

8

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22 March 2020

Jean-François Côté

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Jean-François Côté

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22 March 2020

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Magda Nohemí Hernández-Vásquez

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22 March 2020

Sendi Rafael Adame-García

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22 March 2020

Noumeira Hamoud

3

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22 March 2020

Rony Chidiac

4

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22 March 2020

Guadalupe Reyes-Cruz

5

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22 March 2020

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9 June 2017

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22 March 2020

Journal of Biological Chemistry

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22 March 2020

292

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22 March 2020

29

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22 March 2020

12178-12191

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22 March 2020

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11 June 2022

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Gpr124 is essential for blood-brain barrier integrity in central nervous system disease

1 reference

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Intersectin scaffold proteins and their role in cell signaling and endocytosis.

1 reference

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Gβγ Pathways in Cell Polarity and Migration Linked to Oncogenic GPCR Signaling: Potential Relevance in Tumor Microenvironment

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ELMO1 Directly Interacts with Gβγ Subunit to Transduce GPCR Signaling to Rac1 Activation in Chemotaxis.

1 reference

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The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration

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Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms

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25 August 2018

Intersectin adaptor proteins are associated with actin-regulating protein WIP in invadopodia.

1 reference

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25 August 2018

GPR124 functions as a WNT7-specific coactivator of canonical β-catenin signaling

1 reference

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25 August 2018

Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling

1 reference

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25 August 2018

Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion

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25 August 2018

Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function.

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25 August 2018

G-protein coupled receptor 124 (GPR124) in endothelial cells regulates vascular endothelial growth factor (VEGF)-induced tumor angiogenesis.

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25 August 2018

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Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

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25 August 2018

GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway.

1 reference

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Long-term silencing of intersectin-1s in mouse lungs by repeated delivery of a specific siRNA via cationic liposomes. Evaluation of knockdown effects by electron microscopy

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25 August 2018

Sticky signaling--adhesion class G protein-coupled receptors take the stage

1 reference

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25 August 2018

Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility

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25 August 2018

Rho family GTPases

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25 August 2018

Adhesion G protein-coupled receptors: signaling, pharmacology, and mechanisms of activation

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A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells

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25 August 2018

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/28600358

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M117.780304

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600358%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600358%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600358%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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