(Q50523722)

English

Procyanidin B2 induces Nrf2 translocation and glutathione S-transferase P1 expression via ERKs and p38-MAPK pathways and protect human colonic cells against oxidative stress.

scientific article published in November 2011

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scholarly article

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

Procyanidin B2 induces Nrf2 translocation and glutathione S-transferase P1 expression via ERKs and p38-MAPK pathways and protect human colonic cells against oxidative stress. (English)

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

(+)-procyanidin B2

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

3

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

4

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

author name string

Ildefonso Rodríguez-Ramiro

1

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

Maria Ángeles Martín

5

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

publication date

1 November 2011

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

European Journal of Nutrition

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

51

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

7

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

881-892

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

https://scigraph.springernature.com/pub.10.1007/s00394-011-0269-1

0 references

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Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models

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Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase

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Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cells

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Glutathione transferase pi plays a critical role in the development of lung carcinogenesis following exposure to tobacco-related carcinogens and urethane.

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Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase Pi.

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Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells.

1 reference

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Apple juice intervention modulates expression of ARE-dependent genes in rat colon and liver.

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Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

1 reference

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Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease

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Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element

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Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1.

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Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo

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Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals

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Targeting the redox sensitive Nrf2-Keap1 defense pathway in cardiovascular disease: protection afforded by dietary isoflavones

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Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: relevance for anti-aging intervention

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Cocoa procyanidins attenuate 4-hydroxynonenal-induced apoptosis of PC12 cells by directly inhibiting mitogen-activated protein kinase kinase 4 activity

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Apple polyphenols modulate expression of selected genes related to toxicological defence and stress response in human colon adenoma cells

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GSTT2, a phase II gene induced by apple polyphenols, protects colon epithelial cells against genotoxic damage

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Procyanidin dimers A1, A2, and B2 are absorbed without conjugation or methylation from the small intestine of rats

1 reference

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Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells

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Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK pathway

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inferred from PubMed ID database lookup

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1 reference

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Identifiers

10.1007/S00394-011-0269-1

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/22042007

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