(Q50917552)

25 March 2018

title

Inhibition of caspases primes colon cancer cells for 5-fluorouracil-induced TNF-α-dependent necroptosis driven by RIP1 kinase and NF-κB. (English)

1 reference

25 March 2018

0 references

0 references

1 reference

1 reference

M Oliver Metzig

1

1 reference

25 March 2018

D Fuchs

2

1 reference

25 March 2018

K E Tagscherer

3

1 reference

25 March 2018

H-J Gröne

4

1 reference

25 March 2018

P Schirmacher

5

1 reference

25 March 2018

W Roth

6

1 reference

25 March 2018

language of work or name

English

0 references

publication date

2 November 2015

1 reference

25 March 2018

published in

Oncogene

1 reference

25 March 2018

volume

35

1 reference

25 March 2018

issue

26

1 reference

25 March 2018

page(s)

3399-3409

1 reference

25 March 2018

Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Targeted therapies in colorectal cancer-an integrative view by PPPM

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Killing a cancer: what are the alternatives?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Necroptosis in health and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Control of life-or-death decisions by RIP1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Identification of RIP1 kinase as a specific cellular target of necrostatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

21 January 2018

IAPs: guardians of RIPK1

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Molecular mechanisms of necroptosis: an ordered cellular explosion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

A novel role for RIP1 kinase in mediating TNFα production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Necroptosis, in vivo detection in experimental disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Therapeutic exploitation of necroptosis for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

RIP1, a kinase on the crossroads of a cell's decision to live or die

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Caspases leave the beaten track: caspase-mediated activation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Activation of the NF-kappaB pathway by caspase 8 and its homologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Caspase-8 and caspase-10 activate NF-kappaB through RIP, NIK and IKKalpha kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Regulation of NF-κB signaling by caspases and MALT1 paracaspase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Cathepsins limit macrophage necroptosis through cleavage of Rip1 kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Smac mimetics increase cancer cell response to chemotherapeutics in a TNF-α-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Radiosensitization of solid tumors by Z-VAD, a pan-caspase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

First-in-class pan caspase inhibitor developed for the treatment of liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Determination of apoptotic and necrotic cell death in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

The Gβ5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Metastatic colorectal cancer: integrating irinotecan into combination and sequential chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Shikonin circumvents cancer drug resistance by induction of a necroptotic death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.398

Predictive and prognostic markers in colorectal cancer.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26522725

12 December 2020

inferred from PubMed ID database lookup

Adjuvant Therapy for Stage II and III Colon Cancer: Consensus Report of the International Society of Gastrointestinal Oncology.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26522725

12 December 2020

inferred from PubMed ID database lookup

Clinical trial: the efficacy and safety of oral PF-03491390, a pancaspase inhibitor - a randomized placebo-controlled study in patients with chronic hepatitis C.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26522725

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/ONC.2015.398

1 reference

25 March 2018

release_xamdmmdq4vefdoghokvzjaafhy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xamdmmdq4vefdoghokvzjaafhy

24 November 2022

mapped directly with Wikidata item

1 reference

25 March 2018