(Q51538787)

6 April 2018

title

Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth. (English)

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6 April 2018

author name string

Daniel E Bassi

1

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6 April 2018

Jirong Zhang

2

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6 April 2018

Catherine Renner

3

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6 April 2018

Andres J Klein-Szanto

4

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6 April 2018

publication date

1 September 2016

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6 April 2018

published in

Molecular Carcinogenesis

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6 April 2018

volume

56

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6 April 2018

issue

3

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6 April 2018

page(s)

1182-1188

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6 April 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6166887/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Proprotein convertases: "master switches" in the regulation of tumor growth and progression

1 reference

The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions

21 January 2018

1 reference

Proprotein convertases: lessons from knockouts

21 January 2018

1 reference

Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases

21 January 2018

1 reference

Curbing activation: proprotein convertases in homeostasis and pathology

21 January 2018

1 reference

Furin at the cutting edge: from protein traffic to embryogenesis and disease

21 January 2018

1 reference

Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasis

21 January 2018

1 reference

Molecular Validation of PACE4 as a Target in Prostate Cancer

21 January 2018

1 reference

Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

21 January 2018

1 reference

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

21 January 2018

1 reference

Processing of immunosuppressive pro-TGF-beta 1,2 by human glioblastoma cells involves cytoplasmic and secreted furin-like proteases

21 January 2018

1 reference

Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme

21 January 2018

1 reference

Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions

21 January 2018

1 reference

A novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C.

21 January 2018

1 reference

fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas

21 January 2018

1 reference

Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours

21 January 2018

1 reference

Alterations in gene expression of proprotein convertases in human lung cancer have a limited number of scenarios.

21 January 2018

1 reference

Inhibition of proprotein convertases: approaches to block squamous carcinoma development and progression.

21 January 2018

1 reference

Inhibition of the proprotein convertases represses the invasiveness of human primary melanoma cells with altered p53, CDKN2A and N-Ras genes

21 January 2018

1 reference

Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays.

21 January 2018

1 reference

Therapeutic uses of furin and its inhibitors: a patent review

21 January 2018

1 reference

Novel Furin Inhibitors with Potent Anti-infectious Activity

21 January 2018

1 reference

Phase I trial of "bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancer

21 January 2018

1 reference

Summary of bi-shRNA/GM-CSF augmented autologous tumor cell immunotherapy (FANG™) in advanced cancer of the liver

21 January 2018

1 reference

Pilot Trial of FANG Immunotherapy in Ewing's Sarcoma

21 January 2018

1 reference

Regulation of TGFβ and related signals by precursor processing.

21 January 2018

1 reference

Transforming growth factor-beta regulation of immune responses

21 January 2018

1 reference

Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells

21 January 2018

1 reference

Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases

21 January 2018

1 reference

The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

21 January 2018

1 reference

Increased expression of the pro-protein convertase furin predicts decreased survival in ovarian cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6166887

Furin expression in squamous cell carcinomas of the oral cavity and other sites evaluated by tissue microarray technology

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6166887

The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6166887

Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasiveness.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6166887

2 November 2018

Identifiers

DOI

10.1002/MC.22550

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6 April 2018

PMC publication ID

6166887

0 references

1 reference

6 April 2018