(Q51564147)

7 April 2018

title

Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53. (English)

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7 April 2018

author

Dmitry B Veprintsev

2

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7 April 2018

Alan Fersht

5

object named as

Alan R Fersht

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7 April 2018

Assaf Friedler

1

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7 April 2018

Trevor Rutherford

3

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7 April 2018

Karoly I von Glos

4

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7 April 2018

language of work or name

English

0 references

publication date

20 December 2004

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7 April 2018

Journal of Biological Chemistry

number of pages

9

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based on heuristic

inferred from page(s)

published in

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7 April 2018

volume

280

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7 April 2018

issue

9

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7 April 2018

page(s)

8051-8059

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7 April 2018

cites work

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p53's double life: transactivation-independent repression of homologous recombination.

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Presence of a potent transcription activating sequence in the p53 protein

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Identification of a novel p53 functional domain that is necessary for efficient growth suppression

21 January 2018

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Identification of an additional negative regulatory region for p53 sequence-specific DNA binding

21 January 2018

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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Refined solution structure of the oligomerization domain of the tumour suppressor p53

21 January 2018

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High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

21 January 2018

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Two cellular proteins that bind to wild-type but not mutant p53

21 January 2018

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Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

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Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor

21 January 2018

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Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

21 January 2018

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Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53.

21 January 2018

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Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.

21 January 2018

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Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression

21 January 2018

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Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

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Interaction of p53 with the human Rad51 protein

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Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance

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A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants

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Thermodynamic stability of wild-type and mutant p53 core domain

21 January 2018

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Hot-spot mutants of p53 core domain evince characteristic local structural changes.

21 January 2018

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Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

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NMR-based discovery of lead inhibitors that block DNA binding of the human papillomavirus E2 protein

21 January 2018

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

21 January 2018

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Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

21 January 2018

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Binding of natively unfolded HIF-1alpha ODD domain to p53

21 January 2018

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Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation".

21 January 2018

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Rescuing the function of mutant p53.

21 January 2018

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Cooperative binding of tetrameric p53 to DNA.

21 January 2018

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Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

21 January 2018

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NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2

21 January 2018

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Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains

21 January 2018

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The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411176200

Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411176200

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411176200

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411176200

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411176200

The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411176200

Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411176200

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411176200

Kinetic Instability of p53 Core Domain Mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411176200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411176200

1 reference

7 April 2018

1 reference

7 April 2018