(Q51896081)

17 April 2018

title

Developmental progression of fetal HEB(-/-) precursors to the pre-T-cell stage is restored by HEBAlt. (English)

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17 April 2018

author

Michele K. Anderson

series ordinal

2

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17 April 2018

author name string

Marsela Braunstein

series ordinal

1

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17 April 2018

language of work or name

English

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publication date

27 October 2010

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17 April 2018

European Journal of Immunology

published in

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17 April 2018

volume

40

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17 April 2018

issue

11

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17 April 2018

page(s)

3173-3182

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17 April 2018

The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors

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Functional replacement of the mouse E2A gene with a human HEB cDNA.

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Launching the T-cell-lineage developmental programme

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Essential and partially overlapping role of CD3gamma and CD3delta for development of alphabeta and gammadelta T lymphocytes

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Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo.

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Pleiotropic changes controlled by the pre-T-cell receptor

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Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade

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E and ID proteins branch out.

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Early thymocyte development is regulated by modulation of E2A protein activity

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SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression

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The pT alpha promoter and enhancer are direct targets for transactivation by E box-binding proteins

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ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes

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Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

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7 January 2021

Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon

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7 January 2021

Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development

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7 January 2021

Colocalized transmembrane determinants for ER degradation and subunit assembly explain the intracellular fate of TCR chains

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7 January 2021

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

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7 January 2021

Two distinct steps during thymocyte maturation from CD4-CD8- to CD4+CD8+ distinguished in the early growth response (Egr)-1 transgenic mice with a recombinase-activating gene-deficient background

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Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation

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7 January 2021

Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

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7 January 2021

Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival.

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7 January 2021

T-cell generation by lymph node resident progenitor cells.

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7 January 2021

The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

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7 January 2021

Functional domains of Runx1 are differentially required for CD4 repression, TCRbeta expression, and CD4/8 double-negative to CD4/8 double-positive transition in thymocyte development

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https://api.crossref.org/works/10.1002%2FEJI.201040360

7 January 2021

Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules

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https://api.crossref.org/works/10.1002%2FEJI.201040360

7 January 2021

Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB

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7 January 2021

Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro

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7 January 2021

Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase.

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7 January 2021

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

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7 January 2021

Identifiers

DOI

10.1002/EJI.201040360

1 reference

17 April 2018

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17 April 2018