(Q52011218)

19 April 2018

title

The mechanism of p21-activated kinase 2 autoactivation. (English)

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19 April 2018

author name string

Hao Wu

series ordinal

1

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19 April 2018

Zhi-Xin Wang

series ordinal

2

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19 April 2018

language of work or name

English

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publication date

7 August 2003

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19 April 2018

Journal of Biological Chemistry

published in

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19 April 2018

volume

278

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19 April 2018

issue

43

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19 April 2018

page(s)

41768-41778

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19 April 2018

A thousand and one protein kinases

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Autophosphorylation kinetics of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

p21-activated protein kinase: a crucial component of morphological signaling?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Emerging functions of p21-activated kinases in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Emerging from the Pak: the p21-activated protein kinase family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

The p21Rac/Cdc42-activated kinases (PAKs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

p21-activated kinases: three more join the Pak.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Determinants for substrate phosphorylation by p21-activated protein kinase (gamma-PAK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Catalytic reaction pathway for the mitogen-activated protein kinase ERK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Evaluation of the catalytic mechanism of the p21-activated protein kinase PAK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Protein kinase recognition sequence motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Substrate and pseudosubstrate interactions with protein kinases: determinants of specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Substrates enhance autophosphorylation and activation of p21-activated protein kinase gamma-PAK in the absence of activation loop phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Role of basic residues in the phosphorylation of synthetic peptides by myosin light chain kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Catalytic mechanism of phosphorylase kinase probed by mutational studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Pre-steady-state kinetic analysis of cAMP-dependent protein kinase using rapid quench flow techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Kinetic basis for activation of CDK2/cyclin A by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Transient protein-protein interactions and a random-ordered kinetic mechanism for the phosphorylation of a transcription factor by extracellular-regulated protein kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Kinetics of inactivation of bovine pancreatic ribonuclease A by bromopyruvic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Kinetics of substrate reaction during irreversible modification of enzyme activity for enzymes involving two substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Kinetics of inactivation of aminoacylase by 2-chloromercuri-4-nitrophenol: a new type of complexing inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Activation mechanism and modification kinetics of Chinese hamster dihydrofolate reductase by p-chloromercuribenzoate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

A kinetic approach for the study of protein phosphatase-catalyzed regulation of protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Protein modification: docking sites for kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Activation of an S6/H4 kinase (PAK 65) from human placenta by intramolecular and intermolecular autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Adenosine cyclic 3',5'-monophosphate dependent protein kinase: kinetic mechanism for the bovine skeletal muscle catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Progress curves of reactions catalyzed by unstable enzymes. A theoretical approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

An alternative method for determining inhibition rate constants by following the substrate reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Autophosphorylation and protein kinase activity of p21-activated protein kinase gamma-PAK are differentially affected by magnesium and manganese

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

Dictyostelium myosin heavy chain kinase A subdomains. Coiled-coil and wd repeat roles in oligomerization and substrate targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308196200

21 January 2018

Identifiers

DOI

10.1074/JBC.M308196200

1 reference

19 April 2018

PubMed ID

12907671

1 reference

19 April 2018