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Advances in predictive in vitro models of drug-induced nephrotoxicity.
scientific article published on 6 April 2018
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Europe PubMed Central
PubMed ID
29626199
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4 May 2018
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http://europepmc.org/abstract/MED/29626199
title
Advances in predictive in vitro models of drug-induced nephrotoxicity.
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
29626199
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4 May 2018
reference URL
http://europepmc.org/abstract/MED/29626199
author
Rosalinde Masereeuw
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3
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Europe PubMed Central
PMC publication ID
6013592
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
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9 June 2020
Melissa Little
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4
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Melissa H Little
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Europe PubMed Central
PMC publication ID
6013592
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 June 2020
author name string
Joanne Y-C Soo
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1
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Europe PubMed Central
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6013592
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
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9 June 2020
Jitske Jansen
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2
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Europe PubMed Central
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6013592
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
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9 June 2020
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publication date
6 April 2018
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Europe PubMed Central
PubMed ID
29626199
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4 May 2018
reference URL
http://europepmc.org/abstract/MED/29626199
published in
Nature Reviews Nephrology
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stated in
Europe PubMed Central
PMC publication ID
6013592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 June 2020
volume
14
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stated in
Europe PubMed Central
PMC publication ID
6013592
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
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9 June 2020
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6
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Europe PubMed Central
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6013592
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9 June 2020
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378-393
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9 June 2020
exact match
https://scigraph.springernature.com/pub.10.1038/s41581-018-0003-9
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29 September 2018
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29 September 2018
FGF23 promotes renal calcium reabsorption through the TRPV5 channel
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29 September 2018
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29 September 2018
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29 September 2018
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29 September 2018
Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney
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29 September 2018
Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells
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29 September 2018
Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter
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29 September 2018
Discovery of Dap-3 polymyxin analogues for the treatment of multidrug-resistant Gram-negative nosocomial infections
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29 September 2018
The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: utility of renal specific P450 reductase knockout mouse models
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29 September 2018
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
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29 September 2018
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29 September 2018
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29 September 2018
Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells
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29 September 2018
In vitro evaluation of biomarkers for cisplatin-induced nephrotoxicity using HK-2 human kidney epithelial cells
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29 September 2018
Species differences in drug transporters and implications for translating preclinical findings to humans
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29 September 2018
The directed differentiation of human iPS cells into kidney podocytes
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29 September 2018
Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration.
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29 September 2018
The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule
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29 September 2018
A primary culture of distal convoluted tubules expressing functional thiazide-sensitive NaCl transport.
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29 September 2018
Exploring the transcriptome of ciliated cells using in silico dissection of human tissues
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29 September 2018
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29 September 2018
CYP3A5 genotype-phenotype analysis in the human kidney reveals a strong site-specific expression of CYP3A5 in the proximal tubule in carriers of the CYP3A5*1 allele.
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29 September 2018
In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology
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29 September 2018
Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity
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29 September 2018
Mechanisms of Cisplatin nephrotoxicity
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29 September 2018
Expression of renal distal tubule transporters TRPM6 and NCC in a rat model of cyclosporine nephrotoxicity and effect of EGF treatment.
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29 September 2018
The GUDMAP database--an online resource for genitourinary research
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29 September 2018
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2
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29 September 2018
Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics
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29 September 2018
Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases.
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29 September 2018
Role of organic cation transporters in drug-induced toxicity
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29 September 2018
The Ngal reporter mouse detects the response of the kidney to injury in real time
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29 September 2018
Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity
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29 September 2018
Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies.
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29 September 2018
Next-generation biomarkers for detecting kidney toxicity
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29 September 2018
Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine
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29 September 2018
Neutrophil gelatinase-associated lipocalin and acute kidney injury after cardiac surgery: the effect of baseline renal function on diagnostic performance
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29 September 2018
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29 September 2018
Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters
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29 September 2018
Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis
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29 September 2018
Polymorphism of human cytochrome P450 enzymes and its clinical impact
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29 September 2018
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29 September 2018
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29 September 2018
Amiloride blocks lithium entry through the sodium channel thereby attenuating the resultant nephrogenic diabetes insipidus.
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29 September 2018
Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity
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29 September 2018
Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans
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29 September 2018
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29 September 2018
The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity
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29 September 2018
hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics.
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29 September 2018
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29 September 2018
Tight junction claudins and the kidney in sickness and in health
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29 September 2018
Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
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29 September 2018
Evaluation of putative biomarkers of nephrotoxicity after exposure to ochratoxin a in vivo and in vitro
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29 September 2018
The local and systemic inflammatory transcriptome after acute kidney injury
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29 September 2018
Drug metabolism enzyme expression and activity in primary cultures of human proximal tubular cells
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29 September 2018
The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane.
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29 September 2018
P-glycoprotein-mediated active efflux of the anti-HIV1 nucleoside abacavir limits cellular accumulation and brain distribution
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29 September 2018
Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity
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29 September 2018
Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.
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29 September 2018
Affinity-defining domains in the Na-Cl cotransporter: a different location for Cl- and thiazide binding
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29 September 2018
Lithium treatment induces a marked proliferation of primarily principal cells in rat kidney inner medullary collecting duct
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29 September 2018
A hypothesis linking sodium and lithium reabsorption in the distal nephron
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29 September 2018
Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury.
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29 September 2018
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Amphotericin B.
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29 September 2018
Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice
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29 September 2018
Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury
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29 September 2018
Drug-induced renal failure: update on new medications and unique mechanisms of nephrotoxicity
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29 September 2018
Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration
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29 September 2018
The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.
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29 September 2018
Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney.
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29 September 2018
Probenecid interferes with renal oxidative metabolism: a potential pitfall in its use as an inhibitor of drug transport
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29 September 2018
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.
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29 September 2018
The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1.
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29 September 2018
Active lucifer yellow secretion in renal proximal tubule: evidence for organic anion transport system crossover.
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29 September 2018
Xenobiotic metabolizing enzymes of the kidney
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6013592
retrieved
29 September 2018
Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6013592
retrieved
29 September 2018
Biotransformation and membrane transport in nephrotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6013592
retrieved
29 September 2018
HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6013592
retrieved
29 September 2018
Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6013592
retrieved
30 November 2018
Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6013592
retrieved
30 November 2018
Mechanisms of drug-induced nephrotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation, propagation and characterization of primary tubule cell culture from human kidney
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nephrotic syndrome after oral bisphosphonate (alendronate) administration in a patient with osteoporosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gamma-glutamyl transpeptidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-6 and interleukin-8 levels in the urine of children with renal scarring
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of IL-8 during reperfusion of renal allografts is dependent on ischemic time
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kidney-specific expression of human organic cation transporter 2 (OCT2/SLC22A2) is regulated by DNA methylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Statin-sensitive endocytosis of albumin by glomerular podocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of a MATE protein inhibitor, pyrimethamine, on the renal elimination of metformin at oral microdose and at therapeutic dose in healthy subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41581-018-0003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29626199
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/S41581-018-0003-9
1 reference
stated in
Europe PubMed Central
PMC publication ID
6013592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 June 2020
PMC publication ID
6013592
1 reference
stated in
Europe PubMed Central
PMC publication ID
6013592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 June 2020
PubMed ID
29626199
1 reference
stated in
Europe PubMed Central
PMC publication ID
6013592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29626199%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 June 2020
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