(Q52656784)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609138%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin (English)

1 reference

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28 February 2020

3

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28 February 2020

author name string

Patricia Kent

1

1 reference

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28 February 2020

Nicole Wilkinson

2

1 reference

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28 February 2020

Carine Fillebeen

4

1 reference

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28 February 2020

Konstantinos Gkouvatsos

5

1 reference

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28 February 2020

John Wagner

6

1 reference

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28 February 2020

Marzell Buffler

7

1 reference

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28 February 2020

Christiane Becker

8

1 reference

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28 February 2020

Klaus Schümann

9

1 reference

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28 February 2020

Manuela M Santos

10

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28 February 2020

Kostas Pantopoulos

11

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28 February 2020

publication date

23 January 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609138%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Medicine

28 February 2020

published in

1 reference

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28 February 2020

volume

93

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28 February 2020

issue

5

1 reference

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28 February 2020

page(s)

489-498

1 reference

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https://scigraph.springernature.com/pub.10.1007/s00109-015-1253-7

28 February 2020

exact match

0 references

cites work

Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Systemic iron homeostasis

21 January 2018

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A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

21 January 2018

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Knockout mouse models of iron homeostasis

21 January 2018

1 reference

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Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Hfe acts in hepatocytes to prevent hemochromatosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Altered hepatic BMP signaling pathway in human HFE hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Regulation of cellular iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1253-7

Iron absorption and distribution in TNFΔARE/+ mice, a model of chronic inflammation

21 January 2018

1 reference

12 December 2020

Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis

1 reference

12 December 2020

Molecular basis of HFE-hemochromatosis

1 reference

12 December 2020

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

1 reference

12 December 2020