(Q52828371)

8 May 2018

title

Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates. (English)

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8 May 2018

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4

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8 May 2018

author name string

H H Backus

1

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8 May 2018

H M Pinedo

2

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8 May 2018

D Wouters

3

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8 May 2018

N Molders

5

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8 May 2018

C L van Der Wilt

6

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8 May 2018

C J van Groeningen

7

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8 May 2018

G Jansen

8

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8 May 2018

G J Peters

9

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8 May 2018

language of work or name

English

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publication date

1 September 2000

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8 May 2018

International Journal of Cancer

published in

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8 May 2018

volume

87

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8 May 2018

page(s)

771-778

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8 May 2018

issue

6

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8 May 2018

describes a project that uses

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Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase

1 reference

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Karnofsky memorial lecture. Ode to methotrexate

21 January 2018

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

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Clinical studies with MTA.

21 January 2018

1 reference

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Open, randomized, multicenter trial of raltitrexed versus fluorouracil plus high-dose leucovorin in patients with advanced colorectal cancer. Tomudex Colorectal Cancer Study Group.

21 January 2018

1 reference

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Intrinsic and acquired resistance to methotrexate in acute leukemia.

21 January 2018

1 reference

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Folate-based thymidylate synthase inhibitors as anticancer drugs

21 January 2018

1 reference

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A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

21 January 2018

1 reference

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Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing

21 January 2018

1 reference

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MRP3, an organic anion transporter able to transport anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820000915%2987%3A6%3C771%3A%3AAID-IJC2%3E3.0.CO%3B2-V

Enhancement of the antitumor effects of 5-fluorouracil by folinic acid

21 January 2018

1 reference

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Chemotherapy of Gastrointestinal Cancer

21 January 2018

1 reference

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Transformation of mouse fibroblasts with the oncogenes H-ras OR trk is associated with pronounced changes in drug sensitivity and metabolism

21 January 2018

1 reference

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Pharmacokinetics of Leucovorin Metabolites in Human Plasma as a Function of Dose Administrated Orally and Intravenously

21 January 2018

1 reference

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Preclinical and phase I clinical studies with the nonclassical antifolate thymidylate synthase inhibitor nolatrexed dihydrochloride given by prolonged administration in patients with solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820000915%2987%3A6%3C771%3A%3AAID-IJC2%3E3.0.CO%3B2-V

Impact of schedule on leucovorin potentiation of fluorouracil antitumor activity in dietary folic acid deplete mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820000915%2987%3A6%3C771%3A%3AAID-IJC2%3E3.0.CO%3B2-V

Multitargeted antifolate LY231514 as first-line chemotherapy for patients with advanced non-small-cell lung cancer: A phase II study. National Cancer Institute of Canada Clinical Trials Group

21 January 2018

1 reference

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Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820000915%2987%3A6%3C771%3A%3AAID-IJC2%3E3.0.CO%3B2-V

A dideazatetrahydrofolate analogue lacking a chiral center at C-6, N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]-L-glutamic acid, is an inhibitor of thymidylate synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820000915%2987%3A6%3C771%3A%3AAID-IJC2%3E3.0.CO%3B2-V

Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820000915%2987%3A6%3C771%3A%3AAID-IJC2%3E3.0.CO%3B2-V

Cellular folates prevent polyglutamation of 5, 10-dideazatetrahydrofolate. A novel mechanism of resistance to folate antimetabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820000915%2987%3A6%3C771%3A%3AAID-IJC2%3E3.0.CO%3B2-V

In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820000915%2987%3A6%3C771%3A%3AAID-IJC2%3E3.0.CO%3B2-V

10.1002/1097-0215(20000915)87:6<771::AID-IJC2>3.0.CO;2-V

21 January 2018

Identifiers

DOI

1 reference

8 May 2018

PubMed ID

10956384

1 reference

8 May 2018