(Q52915124)

9 May 2018

title

Rapid multiplex analysis of lipid raft components with single-cell resolution. (English)

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9 May 2018

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6

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9 May 2018

Hannes Stockinger

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9 May 2018

Philipp Schatzlmaier

object named as

Philipp Schatzlmaier

1

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Alexander Zwirzitz

object named as

Alexander Zwirzitz

4

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author name string

Verena Supper

2

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9 May 2018

Lisa Göschl

3

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9 May 2018

Paul Eckerstorfer

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9 May 2018

Johannes B Huppa

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9 May 2018

publication date

22 September 2015

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9 May 2018

published in

Science Signaling

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9 May 2018

volume

8

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9 May 2018

issue

395

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9 May 2018

page(s)

rs11

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9 May 2018

Revitalizing membrane rafts: new tools and insights

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CD4 raft association and signaling regulate molecular clustering at the immunological synapse site

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S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

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TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.

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Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

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Membrane compartmentation is required for efficient T cell activation.

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Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes

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Contamination of nuclear fractions with plasma membrane lipid rafts.

21 January 2018

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Rapid isolation of nuclei from living immune cells by a single centrifugation through a multifunctional lysis gradient

21 January 2018

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Nuclear actin and myosins: life without filaments

21 January 2018

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Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

21 January 2018

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The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl

21 January 2018

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Lipid raft heterogeneity in human peripheral blood T lymphoblasts: a mechanism for regulating the initiation of TCR signal transduction

21 January 2018

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Structure and function of lipid rafts in human activated T cells

21 January 2018

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Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts

21 January 2018

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Caveolin-1 regulates matrix metalloproteinases-1 induction and CD147/EMMPRIN cell surface clustering

21 January 2018

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Tetraspanin CD82 controls the association of cholesterol-dependent microdomains with the actin cytoskeleton in T lymphocytes: relevance to co-stimulation

21 January 2018

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Resistance of cell membranes to different detergents

21 January 2018

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Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Memory CD8+ T cells exhibit increased antigen threshold requirements for recall proliferation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

How the TCR balances sensitivity and specificity for the recognition of self and pathogens.

21 January 2018

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Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells

21 January 2018

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Rapid preparation of nuclei-depleted detergent-resistant membrane fractions suitable for proteomics analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Acetylation and activation of STAT3 mediated by nuclear translocation of CD44.

21 January 2018

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Nuclear trafficking of the epidermal growth factor receptor family membrane proteins

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Quantitative differences in lipid raft components between murine CD4+ and CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis

21 January 2018

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Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation

21 January 2018

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CD4 segregates into specific detergent-resistant T-cell membrane microdomains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells

21 January 2018

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Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib

21 January 2018

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Direct and indirect antibody-induced TX-100 resistance of cell surface antigens

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Cholesterol sensitivity of detergent resistance: a rapid flow cytometric test for detecting constitutive or induced raft association of membrane proteins.

21 January 2018

1 reference

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Proximal human FOXP3 promoter transactivated by NF-kappaB and negatively controlled by feedback loop and SP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Direct observation and quantitative analysis of Lck exchange between plasma membrane and cytosol in living T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

Sequential cooperation of CD2 and CD48 in the buildup of the early TCR signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

The late endosomal transporter CD222 directs the spatial distribution and activity of Lck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAC5584

10.1126/SCISIGNAL.AAC5584

21 January 2018

Identifiers

DOI

1 reference

9 May 2018

1 reference

9 May 2018