(Q24301383)

LCK proto-oncogene, Src family tyrosine kinase

30 December 2023

main subject

1 reference

https://api.crossref.org/works/10.1084/JEM.20022112

GOA release 2020-03-11

1 reference

1 reference

30 December 2023

6

Andre Veillette

Andre

Veillette

1 reference

19 October 2023

1

Dominik Filipp

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732664

30 December 2023

Jenny Zhang

2

Jenny

Zhang

1 reference

19 October 2023

Andrey Shaw

4

author given names

Andrey

author last names

Shaw

1 reference

19 October 2023

Michael Julius

7

author given names

Michael

author last names

Julius

1 reference

19 October 2023

Bernadine L. Leung

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732664

30 December 2023

Steven D. Levin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732664

full work available at URL

30 December 2023

language of work or name

English

0 references

publication date

5 May 2003

0 references

http://jem.rupress.org/content/jem/197/9/1221.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732664

https://europepmc.org/articles/PMC2193969

30 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732664

https://europepmc.org/articles/PMC2193969?pdf=render

30 December 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732664

https://rupress.org/jem/article-pdf/197/9/1221/1709948/jem19791221.pdf

30 December 2023

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1084/JEM.20022112

Journal of Experimental Medicine

30 December 2023

published in

0 references

volume

197

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issue

9

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page(s)

1221-7

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cites work

Protein-tyrosine kinase Pyk2 is involved in interleukin-2 production by Jurkat T cells via its tyrosine 402

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

T cell receptor signaling precedes immunological synapse formation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

T-cell activation through the antigen receptor. Part 1: signaling components, signaling pathways, and signal integration at the T-cell antigen receptor synapse

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Communication between the TCR and integrins: role of the molecular adapter ADAP/Fyb/Slap

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Role for lipid rafts in regulating interleukin-2 receptor signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

The immunological synapse.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

The role of lipid rafts in T cell antigen receptor (TCR) signalling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Functional dissection of the lck proximal promoter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autophosphorylation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193969

Regulation of Lck activity by CD4 and CD28 in the immunological synapse

30 May 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

Lck plays a critical role in Ca(2+) mobilization and CD28 costimulation in mature primary T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56 lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

Fyn can partially substitute for Lck in T lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20022112

21 January 2018

12

2

385

1988

1 reference

https://api.crossref.org/works/10.1084/JEM.20022112

30 December 2023

Identifiers

DOI

10.1084/JEM.20022112

1 reference

release_ba52izpuw5elvd2aipmd6r7gqq

Fatcat ID

0 references

1 reference

1 reference

1 reference