(Q52983396)

10 May 2018

http://europepmc.org/abstract/MED/27115831

title

In Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L Inhibitors. (English)

1 reference

10 May 2018

http://europepmc.org/abstract/MED/27115831

author

Jingyan Ge

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Jun-Seok Lee

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Sijun Pan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Biwei Zhu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Hailong Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Chenyu Wang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Shao Q Yao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

26 April 2016

1 reference

10 May 2018

http://europepmc.org/abstract/MED/27115831

published in

Chemistry—A European Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

7824-7836

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

4 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

hDOT1L links histone methylation to leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Dot1p modulates silencing in yeast by methylation of the nucleosome core

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

New insights to the MLL recombinome of acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Bromo-deaza-SAH: a potent and selective DOT1L inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

DOT1L inhibitor EPZ-5676 displays synergistic antiproliferative activity in combination with standard of care drugs and hypomethylating agents in MLL-rearranged leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Structure-guided DOT1L probe optimization by label-free ligand displacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Mechanism-based profiling of enzyme families

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Target identification of biologically active small molecules via in situ methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Target deconvolution techniques in modern phenotypic profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

From noncovalent to covalent bonds: a paradigm shift in target protein identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Electrophilic natural products and their biological targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Active site profiling reveals coupling between domains in SRC-family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Multiplex imaging and cellular target identification of kinase inhibitors via an affinity-based proteome profiling approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

"Minimalist" cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Cell-based proteome profiling using an affinity-based probe (AfBP) derived from 3-deazaneplanocin A (DzNep).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

The growing impact of click chemistry on drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Cu-catalyzed azide-alkyne cycloaddition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

The use of click chemistry in the emerging field of catalomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

A small-molecule protein-protein interaction inhibitor of PARP1 that targets its BRCT domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Constructing and exploiting the fluorescent protein paintbox (Nobel Lecture).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Fluorescent probes for super-resolution imaging in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Recent progress in strategies for the creation of protein-based fluorescent biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Synthetic fluorescent sensors for studying the cell biology of metals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Enzyme activity--it's all about image

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

Bioorthogonal imaging of aurora kinase A in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

A switchable two-photon membrane tracer capable of imaging membrane-associated protein tyrosine phosphatase activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

A Small-Molecule Probe for Selective Profiling and Imaging of Monoamine Oxidase B Activities in Models of Parkinson's Disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201600259

21 January 2018

Identifiers

DOI

10.1002/CHEM.201600259

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27115831%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference