(Q53418668)

14 May 2018

title

Reduced DNA oxidation in aged prostaglandin H synthase-1 knockout mice (English)

1 reference

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.016

31 August 2024

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Winnie Jeng

1

1 reference

14 May 2018

Annmarie Ramkissoon

2

1 reference

14 May 2018

Peter G. Wells

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21094252

31 August 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21094252

31 August 2024

publication date

18 November 2010

1 reference

14 May 2018

full work available at URL

https://api.elsevier.com/content/article/PII:S0891584910013705?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.016

https://api.elsevier.com/content/article/PII:S0891584910013705?httpAccept=text/plain

31 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.016

Free Radical Biology and Medicine

31 August 2024

published in

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14 May 2018

volume

50

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14 May 2018

issue

4

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14 May 2018

page(s)

550-556

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14 May 2018

Prostaglandin H synthase-1-catalyzed bioactivation of neurotransmitters, their precursors, and metabolites: oxidative DNA damage and electron spin resonance spectroscopy studies

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Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2

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Reduced 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy)-initiated oxidative DNA damage and neurodegeneration in prostaglandin H synthase-1 knockout mice

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Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity

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Inhibition of thalidomide teratogenicity by acetylsalicylic acid: evidence for prostaglandin H synthase-catalyzed bioactivation of thalidomide to a teratogenic reactive intermediate

31 August 2024

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Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-kappa B activity

31 August 2024

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Neuroinflammatory processes in Parkinson's disease.

31 August 2024

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Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease

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Nonsteroidal anti-inflammatory drug use and the risk for Alzheimer's disease: dissecting the epidemiological evidence

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Enzymatic oxidation of dopamine: the role of prostaglandin H synthase

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In vivo autoxidation of dopamine in guinea pig striatum increases with age.

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31 August 2024

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Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis

31 August 2024

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Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

31 August 2024

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DNA oxidation as a potential molecular mechanism mediating drug-induced birth defects: phenytoin and structurally related teratogens initiate the formation of 8-hydroxy-2'-deoxyguanosine in vitro and in vivo in murine maternal hepatic and embryonic

31 August 2024

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31 August 2024

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COX-2: a target for colon cancer prevention

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Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer

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31 August 2024

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Clinical trial of indomethacin in Alzheimer's disease.

31 August 2024

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Risk of Alzheimer's disease and duration of NSAID use.

31 August 2024

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Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease

31 August 2024

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

31 August 2024

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A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

31 August 2024

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Relationship between antioxidant defenses and longevity in different mammalian species

31 August 2024

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31 August 2024

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Expression of 8-oxoguanine DNA glycosylase is reduced and associated with neurofibrillary tangles in Alzheimer's disease brain.

31 August 2024

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Decreased base excision repair and increased helicase activity in Alzheimer's disease brain.

31 August 2024

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DNA damage and chronic neuronal degenerations

31 August 2024

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Oxoguanine glycosylase 1 protects against methamphetamine-enhanced fetal brain oxidative DNA damage and neurodevelopmental deficits

31 August 2024

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Six years of high-level levodopa therapy in severely akinetic parkinsonian patients

31 August 2024

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Levodopa, parkinsonism, and recent memory

31 August 2024

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Oxidative and non-oxidative mechanisms of neuronal cell death and apoptosis by L-3,4-dihydroxyphenylalanine (L-DOPA) and dopamine.

31 August 2024

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L-dopa increases nigral production of hydroxyl radicals in vivo: potential L-dopa toxicity?

31 August 2024

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Motor fluctuations in Parkinson's disease: pathophysiology and treatment

31 August 2024

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31 August 2024

Identifiers

1 reference

14 May 2018

1 reference

14 May 2018