(Q53544041)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Amancio Carnero

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Martinalbo J

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Dubus P

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Malumbres M

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

English

0 references

publication date

18 June 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

7665-7674

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17599058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

55

1 reference

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210578

1 January 2020

exact match

0 references

cites work

Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

The E2F family: specific functions and overlapping interests

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Linking cyclins to transcriptional control.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Tumorigenic activity of p21Waf1/Cip1 in thymic lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

MaRX: an approach to genetics in mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

E2F-Rb complexes regulating transcription of genes important for differentiation and development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

p16INK4a induces an age-dependent decline in islet regenerative potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Rb family proteins as modulators of gene expression and new aspects regarding the interaction with chromatin remodeling enzymes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

To cycle or not to cycle: a critical decision in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Mammalian cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Invasive melanoma in Cdk4-targeted mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021

INK4d-deficient mice are fertile despite testicular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210578

7 January 2021