(Q54232092)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

title

Dengue virus NS2 and NS4: Minor proteins, mammoth roles (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

dengue virus protein NS2A

1 reference

dengue virus protein NS2B

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dengue virus protein NS4A

1 reference

dengue virus protein NS4B

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Sindhoora Bhargavi Gopala Reddy

author

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Wei-Xin Chin

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

author name string

Nanjunda Swamy Shivananju

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

language of work or name

English

0 references

publication date

17 April 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

volume

154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

page(s)

54-63

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

Dengue virus targets the adaptor protein MITA to subvert host innate immunity

24 March 2020

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24 October 2022

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24 October 2022

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Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity

24 October 2022

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Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins

24 October 2022

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Membrane interacting regions of Dengue virus NS2A protein

24 October 2022

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Inhibition of Alpha/Beta Interferon Signaling by the NS4B Protein of Flaviviruses

24 October 2022

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Targeting dengue virus NS4B protein for drug discovery

24 October 2022

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The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development

24 October 2022

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Anti-dengue-virus activity and structure-activity relationship studies of lycorine derivatives

24 October 2022

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Cotranslational membrane insertion of the serine proteinase precursor NS2B-NS3(Pro) of dengue virus type 2 is required for efficient in vitro processing and is mediated through the hydrophobic regions of NS2B.

24 October 2022

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Strategies for development of Dengue virus inhibitors

24 October 2022

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24 October 2022

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Caveolin-1 in lipid rafts interacts with dengue virus NS3 during polyprotein processing and replication in HMEC-1 cells

24 October 2022

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24 October 2022

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Flaviviral Replication Complex: Coordination between RNA Synthesis and 5'-RNA Capping

24 October 2022

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Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant

24 October 2022

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Evidence that flavivirus NS1-NS2A cleavage is mediated by a membrane-bound host protease in the endoplasmic reticulum

24 October 2022

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Closing the door on flaviviruses: Entry as a target for antiviral drug design

24 October 2022

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A structural perspective of the flavivirus life cycle

24 October 2022

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The calmodulin antagonist W-7 (N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride) inhibits DENV infection in Huh-7 cells.

24 October 2022

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Inhibitors of HIV-1 protease: a major success of structure-assisted drug design

24 October 2022

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Cellular vimentin regulates construction of dengue virus replication complexes through interaction with NS4A protein

24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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24 October 2022

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Flaviviral NS4b, chameleon and jack-in-the-box roles in viral replication and pathogenesis, and a molecular target for antiviral intervention

24 October 2022

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Determinants of Dengue Virus NS4A Protein Oligomerization

24 October 2022

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Membrane Topology and Function of Dengue Virus NS2A Protein

24 October 2022

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Approved Antiviral Drugs over the Past 50 Years

24 October 2022

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Recombinant Dengue virus protein NS2B alters membrane permeability in different membrane models

24 October 2022

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The nonstructural protein 3 protease/helicase requires an intact protease domain to unwind duplex RNA efficiently

24 October 2022

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Escape Mutations in NS4B Render Dengue Virus Insensitive to the Antiviral Activity of the Paracetamol Metabolite AM404

24 October 2022

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Progress towards understanding the pathogenesis of dengue hemorrhagic fever.

24 October 2022

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Progress and prospects on DENV protease inhibitors.

24 October 2022

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Mutagenesis of Dengue Virus Protein NS2A Revealed a Novel Domain Responsible for Virus-Induced Cytopathic Effect and Interactions between NS2A and NS2B Transmembrane Segments

24 October 2022

1 reference

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HCV NS2 protein inhibits cell proliferation and induces cell cycle arrest in the S-phase in mammalian cells through down-regulation of cyclin A expression

24 October 2022

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Dengue viral protease interaction with NF-κB inhibitor α/β results in endothelial cell apoptosis and hemorrhage development

24 October 2022

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How the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: the Serine-Histidine-Aspartate Catalytic Triad of α/β-Hydrolase Fold Enzymes.

24 October 2022

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Characterization of dengue virus NS4A and NS4B protein interaction

24 October 2022

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Mapping the Interactions between the NS4B and NS3 proteins of dengue virus

24 October 2022

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Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins

24 October 2022

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Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

24 October 2022

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Role of RNA interference (RNAi) in dengue virus replication and identification of NS4B as an RNAi suppressor

24 October 2022

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Ten years of dengue drug discovery: progress and prospects

24 October 2022

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The search for nucleoside/nucleotide analog inhibitors of dengue virus

24 October 2022

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Glycosylation of dengue virus glycoproteins and their interactions with carbohydrate receptors: possible targets for antiviral therapy.

24 October 2022

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Nordihydroguaiaretic acid (NDGA) inhibits replication and viral morphogenesis of dengue virus

24 October 2022

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An N-terminal amphipathic helix in dengue virus nonstructural protein 4A mediates oligomerization and is essential for replication

24 October 2022

1 reference

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Amino Terminal Region of Dengue Virus NS4A Cytosolic Domain Binds to Highly Curved Liposomes

24 October 2022

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Membrane topology of NS2B of dengue virus revealed by NMR spectroscopy

24 October 2022

1 reference

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Scanning mutagenesis studies reveal a potential intramolecular interaction within the C-terminal half of dengue virus NS2A involved in viral RNA replication and virus assembly and secretion

24 October 2022

1 reference

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A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral Replication

24 October 2022

1 reference

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Towards antiviral therapies for treating dengue virus infections.

24 October 2022

1 reference

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Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.

24 October 2022

1 reference

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The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner

24 October 2022

1 reference

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Structural platform for the autolytic activity of an intact NS2B-NS3 protease complex from dengue virus

24 October 2022

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2018.04.008

NS4A regulates the ATPase activity of the NS3 helicase: a novel cofactor role of the non-structural protein NS4A from West Nile virus

24 October 2022

1 reference

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Secondary structure and membrane topology of dengue virus NS4A protein in micelles

24 October 2022

1 reference

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Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site

24 October 2022

1 reference

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Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase

24 October 2022

1 reference

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Cleavage of dengue virus NS1-NS2A requires an octapeptide sequence at the C terminus of NS1

24 October 2022

1 reference

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10.1016/J.BCP.2018.04.008

24 October 2022

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674002%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference