(Q54277677)

27 May 2018

title

Conformation-dependent epitopes recognized by prion protein antibodies probed using mutational scanning and deep sequencing (English)

1 reference

27 May 2018

0 references

1 reference

deep mutational scanning

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author

Kyle M Doolan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451031%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

David W Colby

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451031%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Kyle M Doolan

1

1 reference

27 May 2018

David W Colby

2

1 reference

27 May 2018

language of work or name

English

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publication date

7 November 2014

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27 May 2018

number of pages

13

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Journal of Molecular Biology

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451031%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

427

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451031%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451031%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

328-340

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451031%20AND%20SRC:MED&resulttype=core&format=json

A Benchmark Study on Error Assessment and Quality Control of CCS Reads Derived from the PacBio RS

10 June 2020

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28 May 2018

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28 May 2018

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28 May 2018

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Characterization of conformation-dependent prion protein epitopes

28 May 2018

1 reference

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Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

28 May 2018

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Methionine oxidation perturbs the structural core of the prion protein and suggests a generic misfolding pathway

28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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PrP(Sc)-specific antibodies with the ability to immunodetect prion oligomers.

28 May 2018

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28 May 2018

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28 May 2018

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Conformation-dependent high-affinity monoclonal antibodies to prion proteins

28 May 2018

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Folding kinetics of the human prion protein probed by temperature jump.

28 May 2018

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Epitope mapping using ribosome display in a reconstituted cell-free protein synthesis system

28 May 2018

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Crystal structure of human prion protein bound to a therapeutic antibody

28 May 2018

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Real-time DNA sequencing from single polymerase molecules

28 May 2018

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Isolating and engineering human antibodies using yeast surface display

28 May 2018

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The charge structure of helix 1 in the prion protein regulates conversion to pathogenic PrPSc

28 May 2018

1 reference

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An aggregation-specific enzyme-linked immunosorbent assay: detection of conformational differences between recombinant PrP protein dimers and PrP(Sc) aggregates

28 May 2018

1 reference

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Reducing mutational bias in random protein libraries

28 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Fine epitope mapping of anti-epidermal growth factor receptor antibodies through random mutagenesis and yeast surface display

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Domain-level antibody epitope mapping through yeast surface display of epidermal growth factor receptor fragments

28 May 2018

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Stereochemistry of polypeptide chain configurations

28 May 2018

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Affinity maturation of Fab antibody fragments by fluorescent-activated cell sorting of yeast-displayed libraries

28 May 2018

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Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

28 May 2018

1 reference

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Epitope mapping and affinity purification of monospecific antibodies by Escherichia coli cell surface display of gene-derived random peptide libraries

28 May 2018

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Crystal structure of the human prion protein reveals a mechanism for oligomerization

28 May 2018

1 reference

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28 May 2018

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Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein.

28 May 2018

1 reference

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Mapping the prion protein using recombinant antibodies

28 May 2018

1 reference

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Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments

28 May 2018

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Prion (PrPSc)-specific epitope defined by a monoclonal antibody

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Yeast surface display for screening combinatorial polypeptide libraries

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

In vitro selection and evolution of functional proteins by using ribosome display

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

NMR structure of the mouse prion protein domain PrP(121-231)

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

28 May 2018

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Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred

28 May 2018

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Probing the conformation of the prion protein within a single amyloid fibril using a novel immunoconformational assay.

28 May 2018

1 reference

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Protein conformation significantly influences immune responses to prion protein.

13 August 2018

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Engineering antibody affinity by yeast surface display.

13 August 2018

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Cell surface expression of the prion protein in yeast does not alter copper utilization phenotypes

13 August 2018

1 reference

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The effect of disease-associated mutations on the folding pathway of human prion protein

13 August 2018

1 reference

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The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885637

Binding of disease-associated prion protein to plasminogen.

13 August 2018

1 reference

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Immunogenicity and epitope mapping of foreign sequences via genetically engineered filamentous phage

13 August 2018

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Monoclonal antibodies inhibit prion replication and delay the development of prion disease

13 August 2018

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12 December 2020

Secretion-and-capture cell-surface display for selection of target-binding proteins

1 reference

12 December 2020

An integrating vector for tunable, high copy, stable integration into the dispersed Ty delta sites of Saccharomyces cerevisiae

1 reference

12 December 2020

Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus

1 reference

12 December 2020

Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc

1 reference

12 December 2020

Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae

1 reference

12 December 2020

Production and Characterization of a Panel of Monoclonal Antibodies Against Native Human Cellular Prion Protein

1 reference

12 December 2020

10.1016/J.JMB.2014.10.024

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451031%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451031%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

25451031

1 reference