(Q54445142)

English

Protective effects of hesperidin against amyloid-β (Aβ) induced neurotoxicity through the voltage dependent anion channel 1 (VDAC1)-mediated mitochondrial apoptotic pathway in PC12 cells.

scientific article published on 9 March 2013

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

Protective effects of hesperidin against amyloid-β (Aβ) induced neurotoxicity through the voltage dependent anion channel 1 (VDAC1)-mediated mitochondrial apoptotic pathway in PC12 cells. (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

1 reference

based on heuristic

inferred from title

toxic encephalopathy

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Dong-Mei Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

San-Qiang Li

2

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

Xiao-Ying Zhu

3

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

Yong Wang

4

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

Wen-Lan Wu

5

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

Xiao-Juan Zhang

6

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

publication date

9 March 2013

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

Neurochemical Research

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

38

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

5

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

1034-1044

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

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Pathways towards and away from Alzheimer's disease

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21 January 2018

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

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21 January 2018

Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death

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Abeta oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures

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Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease

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Effect of β-amyloid (25-35) on mitochondrial function and expression of mitochondrial permeability transition pore proteins in rat hippocampal neurons

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Antioxidant activity of the flavonoid hesperidin in chemical and biological systems

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Hesperidin attenuates benzo[alpha] pyrene-induced testicular toxicity in rats via regulation of oxidant/antioxidant balance

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Hesperidin ameliorates immobilization-stress-induced behavioral and biochemical alterations and mitochondrial dysfunction in mice by modulating nitrergic pathway

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Hesperidin pre-treatment attenuates NO-mediated cerebral ischemic reperfusion injury and memory dysfunction

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21 January 2018

Cytoprotective effects of hesperetin and hesperidin against amyloid β-induced impairment of glucose transport through downregulation of neuronal autophagy

1 reference

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21 January 2018

Taurine protects transformed rat retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction

1 reference

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21 January 2018

Bcl2 mitigates Ca2+ entry and mitochondrial Ca2+ overload through downregulation of L-type Ca2+ channels in PC12 cells

1 reference

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21 January 2018

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

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21 January 2018

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 reference

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21 January 2018

Amyloid fibril toxicity in Alzheimer's disease and diabetes

1 reference

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21 January 2018

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

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Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus

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Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta

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21 January 2018

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway.

1 reference

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21 January 2018

Uncovering the role of VDAC in the regulation of cell life and death

1 reference

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21 January 2018

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

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21 January 2018

Estradiol protects against beta-amyloid (25-35)-induced toxicity in SK-N-SH human neuroblastoma cells

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21 January 2018

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

1 reference

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21 January 2018

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

1 reference

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21 January 2018

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

1 reference

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21 January 2018

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

1 reference

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21 January 2018

Mitochondrial aging and dysfunction in Alzheimer's disease

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21 January 2018

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

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21 January 2018

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

1 reference

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21 January 2018

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

1 reference

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The role of Abeta-induced calcium dysregulation in the pathogenesis of Alzheimer's disease.

1 reference

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Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

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Hesperidin alleviates acetaminophen induced toxicity in Wistar rats by abrogation of oxidative stress, apoptosis and inflammation

1 reference

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Neuroprotective effects of the citrus flavanones against H2O2-induced cytotoxicity in PC12 cells

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Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome

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The voltage-dependent anion channel-1 modulates apoptotic cell death.

1 reference

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A role for voltage-dependent anion channel Vdac1 in polyglutamine-mediated neuronal cell death

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Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding.

1 reference

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Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo

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Hexokinase II: the integration of energy metabolism and control of apoptosis

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In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death

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Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

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Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β.

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Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m

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Hesperetin protects testicular toxicity of doxorubicin in rat: Role of NFκB, p38 and caspase-3

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

The key role of mitochondria in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23475456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological effects of hesperidin, a citrus flavonoid. (Note I): antiinflammatory and analgesic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23475456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced expression of the voltage-dependent anion channel 1 (VDAC1) in Alzheimer's disease transgenic mice: an insight into the pathogenic effects of amyloid-β.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23475456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible nitric oxide mechanism in the protective effect of hesperidin against ischemic reperfusion cerebral injury in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23475456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/23475456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-013-1013-4

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/23475456

ResearchGate publication ID

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