(Q54503120)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22714993%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling (English)

1 reference

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5 February 2020

1 reference

acute myeloid leukemia

1 reference

7

1 reference

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5 February 2020

Jean-Antoine Girault

10

1 reference

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5 February 2020

Gaetan Chicanne

2

1 reference

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5 February 2020

Claire Racaud-Sultan

11

1 reference

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5 February 2020

8

Connie Eaves

1 reference

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5 February 2020

author name string

Mathieu Despeaux

1

1 reference

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5 February 2020

Evelyne Rouer

3

1 reference

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5 February 2020

Fabienne De Toni-Costes

4

1 reference

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5 February 2020

Jessica Bertrand

5

1 reference

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5 February 2020

Véronique Mansat-De Mas

6

1 reference

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5 February 2020

Bernard Payrastre

9

1 reference

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5 February 2020

publication date

1 August 2012

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5 February 2020

1 reference

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5 February 2020

volume

30

1 reference

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5 February 2020

issue

8

1 reference

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5 February 2020

page(s)

1597-1610

1 reference

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RAFTK/Pyk2-mediated cellular signalling

5 February 2020

cites work

1 reference

Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasis

21 January 2018

1 reference

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

21 January 2018

1 reference

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.

21 January 2018

1 reference

Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells

21 January 2018

1 reference

Organization and post-transcriptional processing of focal adhesion kinase gene

21 January 2018

1 reference

Alternatively spliced focal adhesion kinase in rat brain with increased autophosphorylation activity

21 January 2018

1 reference

Autophosphorylation of Tyr397 and its phosphorylation by Src-family kinases are altered in focal-adhesion-kinase neuronal isoforms

21 January 2018

1 reference

Alternative splicing controls the mechanisms of FAK autophosphorylation

21 January 2018

1 reference

Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells.

21 January 2018

1 reference

Phosphatidylinositol-3-kinase activation mediates proline-rich tyrosine kinase 2 phosphorylation and recruitment to beta1-integrins in human CD34+ cells

21 January 2018

1 reference

Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells

21 January 2018

1 reference

Expression of focal adhesion kinase in acute myeloid leukemia is associated with enhanced blast migration, increased cellularity, and poor prognosis

21 January 2018

1 reference

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products

21 January 2018

1 reference

21 January 2018

1 reference

How the niche regulates hematopoietic stem cells.

21 January 2018

1 reference

The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

21 January 2018

1 reference

β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells

21 January 2018

1 reference

Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation

21 January 2018

1 reference

The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.

21 January 2018

1 reference

Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia

21 January 2018

1 reference

Expression of beta-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis

21 January 2018

1 reference

Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells

21 January 2018

1 reference

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

21 January 2018

1 reference

Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis

21 January 2018

1 reference

Osteopontin induces beta-catenin signaling through activation of Akt in prostate cancer cells

21 January 2018

1 reference

A role for Wnt signalling in self-renewal of haematopoietic stem cells

21 January 2018

1 reference

Wnt proteins are lipid-modified and can act as stem cell growth factors

21 January 2018

1 reference

Gene expression profiles of pancreatic cancer and stromal desmoplasia

21 January 2018

1 reference

WNT5A expression increases during melanoma progression and correlates with outcome

21 January 2018

1 reference

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

21 January 2018

1 reference

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

21 January 2018

1 reference

Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2.

21 January 2018

1 reference

Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

21 January 2018

1 reference

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

21 January 2018

1 reference

Cellular characterization of a novel focal adhesion kinase inhibitor

21 January 2018

1 reference

Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex

21 January 2018

1 reference

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

21 January 2018

1 reference

Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity

21 January 2018

1 reference

Phosphatidylinositol 3-kinase signaling does not activate the wnt cascade

21 January 2018

1 reference

Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo.

21 January 2018

1 reference

Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation

21 January 2018

1 reference

Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.

21 January 2018

1 reference

Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect

21 January 2018

1 reference

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells

21 January 2018

1 reference

Critical features of FAK-expressing AML bone marrow microenvironment through leukemia stem cell hijacking of mesenchymal stromal cells.

21 January 2018

1 reference

Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate

21 January 2018

1 reference

A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia.

21 January 2018

1 reference

p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal

21 January 2018

1 reference

Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites

21 January 2018

1 reference

p53 regulates FAK expression in human tumor cells

21 January 2018

1 reference