(Q55035903)

16 June 2018

title

A novel specific role for I kappa B kinase complex-associated protein in cytosolic stress signaling. (English)

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16 June 2018

author

Marja Jäättelä

5

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16 June 2018

Mads Lerdrup

object named as

Mads Lerdrup

3

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Christian Holmberg

object named as

Christian Holmberg

1

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Ami Aronheim

object named as

Ami Aronheim

6

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author name string

Sigal Katz

2

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16 June 2018

Thomas Herdegen

4

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16 June 2018

Tuula Kallunki

7

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16 June 2018

language of work or name

English

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publication date

10 June 2002

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16 June 2018

Journal of Biological Chemistry

number of pages

11

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based on heuristic

inferred from page(s)

published in

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16 June 2018

volume

277

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16 June 2018

page(s)

31918-31928

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16 June 2018

issue

35

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16 June 2018

IKAP is a scaffold protein of the IkappaB kinase complex

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Purification and characterization of the human elongator complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200719200

Familial dysautonomia is caused by mutations of the IKAP gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200719200

Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia

21 January 2018

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Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

21 January 2018

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Diverse functions of JNK signaling and c-Jun in stress response and apoptosis

21 January 2018

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Transcription factor ATF2 regulation by the JNK signal transduction pathway

21 January 2018

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p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system

21 January 2018

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Signal transduction by the JNK group of MAP kinases

21 January 2018

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Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

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Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

21 January 2018

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The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

21 January 2018

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Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

21 January 2018

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

21 January 2018

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JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

21 January 2018

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Signal transduction by tumor necrosis factor mediated by JNK protein kinases

21 January 2018

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The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Organization and regulation of mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

AP-1 function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

A cytoplasmic inhibitor of the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

A mammalian scaffold complex that selectively mediates MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

A non-enzymatic p21 protein inhibitor of stress-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Rb protein down-regulates the stress-activated signals through inhibiting c-Jun N-terminal kinase/stress-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Ras signaling pathway for analysis of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

The ras recruitment system, a novel approach to the study of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Expression cloning of a human DNA repair gene involved in xeroderma pigmentosum group C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

The TPR snap helix: a novel protein repeat motif from mitosis to transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Signal transduction: hanging on a scaffold.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

The JIP group of mitogen-activated protein kinase scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Structural gene for beta-nerve growth factor not defective in familial dysautonomia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Amino-acid substitutions in the IKAP gene product significantly increase risk for bronchial asthma in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200719200

21 January 2018

Identifiers

DOI

10.1074/JBC.M200719200

1 reference

16 June 2018

PubMed ID

12058026

1 reference

16 June 2018