(Q55073016)

17 June 2018

title

Microglia in Alzheimer's Disease: Activated, Dysfunctional or Degenerative. (English)

1 reference

17 June 2018

0 references

1 reference

Victoria Navarro

1

1 reference

17 June 2018

Elisabeth Sanchez-Mejias

2

1 reference

17 June 2018

Sebastian Jimenez

3

1 reference

17 June 2018

Clara Muñoz-Castro

4

1 reference

17 June 2018

Raquel Sanchez-Varo

5

1 reference

17 June 2018

Jose C Davila

6

1 reference

17 June 2018

Marisa Vizuete

7

1 reference

17 June 2018

Antonia Gutierrez

8

1 reference

17 June 2018

Javier Vitorica

9

1 reference

17 June 2018

publication date

11 May 2018

1 reference

17 June 2018

Frontiers in Aging Neuroscience

published in

1 reference

17 June 2018

volume

10

1 reference

17 June 2018

page(s)

140

1 reference

17 June 2018

Creative Commons Attribution 4.0 International

copyright license

start time

11 May 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease

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Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer's disease

18 June 2018

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A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

18 June 2018

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TREM2, Microglia, and Neurodegenerative Diseases.

18 June 2018

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Elucidating the Role of TREM2 in Alzheimer's Disease

18 June 2018

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A novel mutation in TREM2 gene causing Nasu-Hakola disease and review of the literature

18 June 2018

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Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

18 June 2018

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Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration

18 June 2018

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18 June 2018

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TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

18 June 2018

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Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond

18 June 2018

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18 June 2018

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Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System

18 June 2018

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Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.

18 June 2018

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Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology

18 June 2018

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R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study

18 June 2018

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Immune attack: the role of inflammation in Alzheimer disease.

18 June 2018

1 reference

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Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

18 June 2018

1 reference

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Neuroinflammation in Alzheimer's disease

18 June 2018

1 reference

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TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

18 June 2018

1 reference

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Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains

18 June 2018

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18 June 2018

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Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer's disease pathology

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer's-like disease progression

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

A phenotypic change but not proliferation underlies glial responses in Alzheimer disease

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

TREM2 Variants in Alzheimer's Disease

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

18 June 2018

Physiology of microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Brain and bone damage in KARAP/DAP12 loss-of-function mice correlate with alterations in microglia and osteoclast lineages.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Toward a New Concept of Alzheimer's Disease Models: A Perspective from Neuroinflammation.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Early and Late CNS Inflammation in Alzheimer's Disease: Two Extremes of a Continuum?

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Microglia in Alzheimer's disease.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

A new fate mapping system reveals context-dependent random or clonal expansion of microglia

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Characteristic microglial features in patients with hereditary diffuse leukoencephalopathy with spheroids.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Microglial pathology in Down syndrome.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Extracellular amyloid-beta and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1(M146L)/APP(751SL) mice

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Microglia in Alzheimer's disease

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5958192

Immunohistochemical characterization of microglia in Nasu-Hakola disease brains

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29867449

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.3389/FNAGI.2018.00140

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ilfraoiau5bhrbxmi4frstdrz4

30 July 2022

release_ilfraoiau5bhrbxmi4frstdrz4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ilfraoiau5bhrbxmi4frstdrz4

30 July 2022

https://api.fatcat.wiki/v0/release/ilfraoiau5bhrbxmi4frstdrz4

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/ilfraoiau5bhrbxmi4frstdrz4

1 reference

30 July 2022